ArticleJournal of clinical medicine2019
Lower Plasma Magnesium, Measured by Nuclear Magnetic Resonance Spectroscopy, is Associated with Increased Risk of Developing Type 2 Diabetes Mellitus in Women: Results from a Dutch Prospective Cohort Study.
Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Oral magnesium supplements and insulin resistance in individuals with diabetes and pre-diabetes: an updated systematic review and meta-analysis of randomized controlled trials.BMC nutrition · 2026Pooled it
- Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus:Sultan Qaboos University medical journal · 2025Pooled it
- A Universal Framework for Blood Ionome Extraction and Intelligent Quality Control inAnalytical chemistry · 2026Article
- The association between serum magnesium levels and hypertensive disorders of pregnancy.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025Article
- Article
- Micronutrient deficiencies and new-onset atrial fibrillation in a community-based cohort: data from PREVEND.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Observational
- Sex- and age-specific associations of serum essential elements with diabetes among the Chinese adults: a community-based cross-sectional study.Nutrition & metabolism · 2024Article
- Review
- Association of diuretic use with increased risk for long-term post-transplantation diabetes mellitus in kidney transplant recipients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022Article
- Article
- Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.Nutrients · 2021Review
- Sarcopenia Index as a Predictor of Clinical Outcomes in Older Patients with Coronary Artery Disease.Journal of clinical medicine · 2020Article
- Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease.Antioxidants (Basel, Switzerland) · 2020Review
- Ketone Bodies Are Mildly Elevated in Subjects with Type 2 Diabetes Mellitus and Are Inversely Associated with Insulin Resistance as Measured by the Lipoprotein Insulin Resistance Index.Journal of clinical medicine · 2020Article
- Hypomagnesaemia and its determinants in a contemporary primary care cohort of persons with type 2 diabetes.Endocrine · 2020Observational
- Blood MgDiabetologia · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow circulating magnesium (Mg) is associated with an increased risk of developing type 2 diabetes mellitus (T2DM). We aimed to study the performance of a nuclear magnetic resonance (NMR)-based assay that quantifies ionized Mg in EDTA plasma samples and prospectively investigate the association of Mg with the risk of T2DM.
methodsThe analytic performance of an NMR-based assay for measuring plasma Mg was evaluated. We studied 5747 subjects free of T2DM at baseline in the Prevention of Renal and Vascular End-stage Disease (PREVEND) study.
resultsPassing⁻Bablok regression analysis, comparing NMR-measured ionized Mg with total Mg measured by the Roche colorimetric assay, produced a correlation of
conclusionLower NMR-measured plasma ionized Mg was independently associated with a higher risk of developing T2DM in women, but not in men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.