Evidence map›Paper›PMID 30717284›Full record

ArticleGenes2019

Using Decision Tree Aggregation with Random Forest Model to Identify Gut Microbes Associated with Colorectal Cancer.

Dongmei Ai, Hongfei Pan, Rongbao Han, Xiaoxin Li, Gang Liu, Li C Xia

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

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  8. Intratumor microbiota and colorectal cancer: Comprehensive and lucid review.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dongmei AiBasic Experimental of Natural Science, University of Science and Technology Beijing, Beijing 100083, China. aidongmei@ustb.edu.cn.
Hongfei PanSchool of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China. 18813128340@163.com.
Rongbao HanSchool of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China. rongbaohan@163.com.
Xiaoxin LiSchool of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China. lixiaoxinustb@sina.com.
Gang LiuSchool of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China. s20180807@xs.ustb.edu.cn.
Li C XiaDepartment of Medicine, Stanford University School of Medicine, 269 Campus Dr., Stanford, CA 94305, USA. l.c.xia@stanford.edu.
University of Science and Technology Beijing · CNStanford University · US

Funding

Foundation for the National Institutes of Health HG006137-07
6 · The paper itself

Abstract

The imbalance of human gut microbiota has been associated with colorectal cancer. In recent years, metagenomics research has provided a large amount of scientific data enabling us to study the dedicated roles of gut microbes in the onset and progression of cancer. We removed unrelated and redundant features during feature selection by mutual information. We then trained a random forest classifier on a large metagenomics dataset of colorectal cancer patients and healthy people assembled from published reports and extracted and analysed the information from the learned decision trees. We identified key microbial species associated with colorectal cancers. These microbes included

Indexed as

AlgorithmsGastrointestinal MicrobiomeMetagenomeBacillotaColorectal NeoplasmsFusobacteriumHumansPorphyromonasSequence Analysis, DNAcolorectal cancermicrobial community analysismicrobial relative abundancesmutual informationrandom forest

Identifiers

PMID30717284
PMCPMC6410271
OpenAlexW2912871672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.