Evidence map›Paper›PMID 30717235›Full record

ArticleMarine drugs2019

Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta

Sofia-Eléna Motuhi, Omid Feizbakhsh, Béatrice Foll-Josselin, Blandine Baratte, Claire Delehouzé, Arnaud Cousseau, Xavier Fant, Jeannette Chloë Bulinski, Claude Elisabeth Payri, Sandrine Ruchaud and 2 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 4 countries.

Sofia-Eléna MotuhiUMR ENTROPIE (IRD-Université de La Réunion-CNRS), Laboratoire d'Excellence Labex-CORAIL, Institut de Recherche pour le Développement (IRD), BP A5, 98848 Nouméa CEDEX, New Caledonia, France. sofia-elena.motuhi@sb-roscoff.fr.
Omid FeizbakhshSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. omid.feizbakhsh@sb-roscoff.fr.
Béatrice Foll-JosselinSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. beatrice.josselin@sb-roscoff.fr.
Blandine BaratteSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. baratte@sb-roscoff.fr.ORCID 0000-0002-2064-9558
Claire DelehouzéSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. claire.delehouze@gmail.com.
Arnaud CousseauSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. arnaud.cousseau@unice.fr.
Xavier FantSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. xavierfant@yahoo.fr.
Jeannette Chloë BulinskiSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. jcb4@columbia.edu.
Claude Elisabeth PayriUMR ENTROPIE (IRD-Université de La Réunion-CNRS), Laboratoire d'Excellence Labex-CORAIL, Institut de Recherche pour le Développement (IRD), BP A5, 98848 Nouméa CEDEX, New Caledonia, France. claude.payri@ird.fr.
Sandrine RuchaudSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. sandrine.ruchaud@sb-roscoff.fr.ORCID 0000-0002-4606-6625
Mohamed MehiriUMR 7272 CNRS, Marine Natural Products Team, Nice Institute of Chemistry (ICN), University Nice Sophia Antipolis, Parc Valrose, 02 F-06108 Nice CEDEX, France. Mohamed.MEHIRI@univ-cotedazur.fr.
Stéphane BachSorbonne Université, CNRS, USR 3151, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, CS 90074, 29688 Roscoff CEDEX, France. bach@sb-roscoff.fr.ORCID 0000-0002-7186-7483
Centre National de la Recherche Scientifique · FR

Funding

ANR/Investissements d'Avenir program via the OCEANOMICs project ANR-11-BTBR-0008Cancéropôle PACA Marine Natural ProductsEuropean Union's Horizon 2020 research and innovation programme 654008Government of New Caledonia Thesis GrantInstitut National Du Cancer Marine Natural ProductsInstitut National Du Cancer NECROTRAILLigue Contre le Cancer CSIRGORégion Bretagne ARED Fellowship program
6 · The paper itself

Abstract

The marine α-pyrone macrolide neurymenolide A was previously isolated from the Fijian red macroalga,

Indexed as

ApoptosisBone NeoplasmsCell Line, TumorDrug Screening Assays, AntitumorHep G2 CellsHumansK562 CellsMacrolidesMCF-7 CellsMicrotubulesMitosisNecrosisOsteosarcomaPyronesRhodophytaSpindle ApparatusMacrolidesneurymenolide APyronesapoptosismitotic catastrophemitotic spindle poisonnecrosisneurymenolide ANew CaledoniaPhacelocarpus neurymenioidesRhodophyta

Identifiers

PMID30717235
PMCPMC6410418
OpenAlexW2914380193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.