Evidence map›Paper›PMID 30717229›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Poly(vinylidene fluoride) Composite Nanofibers Containing Polyhedral Oligomeric Silsesquioxane⁻Epigallocatechin Gallate Conjugate for Bone Tissue Regeneration.

Hyo-Geun Jeong, Yoon-Soo Han, Kyung-Hye Jung, Young-Jin Kim

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyo-Geun JeongDepartment of Biomedical Engineering, Daegu Catholic University, Gyeongsan 38430, Korea. jhg2833@empal.com.
Yoon-Soo HanDepartment of Advanced Materials and Chemical Engineering, Daegu Catholic University, Gyeongsan 38430, Korea. yshancu@cu.ac.kr.
Kyung-Hye JungDepartment of Advanced Materials and Chemical Engineering, Daegu Catholic University, Gyeongsan 38430, Korea. khjung@cu.ac.kr.
Young-Jin KimDepartment of Biomedical Engineering, Daegu Catholic University, Gyeongsan 38430, Korea. yjkim@cu.ac.kr.

Funding

Catholic University of Daegu 2017
6 · The paper itself

Abstract

To provide adequate conditions for the regeneration of damaged bone, it is necessary to develop piezoelectric porous membranes with antioxidant and anti-inflammatory activities. In this study, composite nanofibers comprising poly(vinylidene fluoride) (PVDF) and a polyhedral oligomeric silsesquioxane⁻epigallocatechin gallate (POSS⁻EGCG) conjugate were fabricated by electrospinning methods. The resulting composite nanofibers showed three-dimensionally interconnected porous structures. Their average diameters, ranging from 936 ± 223 nm to 1094 ± 394 nm, were hardly affected by the addition of the POSS⁻EGCG conjugate. On the other hand, the piezoelectric β-phase increased significantly from 77.4% to 88.1% after adding the POSS⁻EGCG conjugate. The mechanical strength of the composite nanofibers was ameliorated by the addition of the POSS⁻EGCG conjugate. The results of in vitro bioactivity tests exhibited that the proliferation and differentiation of osteoblasts (MC3T3-E1) on the nanofibers increased with the content of POSS⁻EGCG conjugate because of the improved piezoelectricity and antioxidant and anti-inflammatory properties of the nanofibers. All results could suggest that the PVDF composite nanofibers were effective for guided bone regeneration.

Indexed as

antioxidant activitybone regenerationcomposite nanofiberpiezoelectricitypoly(vinylidene fluoride)

Identifiers

PMID30717229
PMCPMC6409983

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.