Evidence map›Paper›PMID 30716702›Full record

ArticleInternational journal of surgery case reports2019

Successful surgical management of non-perforating acute appendicitis with septic disseminated intravascular coagulation: A case report and review of the literature.

Toshiaki Komo, Toshihiko Kohashi, Yoshirou Aoki, Jun Hihara, Koichi Oishi, Noriaki Tokumoto, Mikihiro Kanou, Akira Nakashima, Manabu Shimomura, Masashi Miguchi and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Toshiaki KomoDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan. Electronic address: toshiaki-k-tkt@car.ocn.ne.jp.
Toshihiko KohashiDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan; Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute Biomedical & Health Sciences, Hiroshima University, Japan. Electronic address: tkohashi0303@gmail.com.
Yoshirou AokiDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Jun HiharaDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Koichi OishiDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Noriaki TokumotoDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Mikihiro KanouDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Akira NakashimaDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Manabu ShimomuraDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Masashi MiguchiDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Hidenori MukaidaDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Naoki HirabayashiDepartment of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Hiroshima City Asa Citizens Hospital · JPHiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPerforating appendicitis and abscess-forming appendicitis may cause septic disseminated intravascular coagulation (DIC). However, non-perforating acute appendicitis with septic DIC is extremely rare. PRESENTATION OF CASE: A 67-year-old man was referred to our hospital one day after starting oral antibiotic treatment for acute appendicitis. Physical examination revealed only slight spontaneous abdominal pain without tenderness and peritoneal irritation. Contrast-enhanced computed tomography demonstrated an enlarged appendix (10 mm in diameter) without fecalith, ascites, intraperitoneal free air, and abscess. There was no evidence of perforating appendicitis. Laboratory analysis revealed septic DIC. The patient was diagnosed with non-perforating acute appendicitis with septic DIC. The patient was distressed regarding whether he should be treated conservatively with an antibiotics-first strategy or undergo an appendectomy. Ultimately, a laparoscopic appendectomy was performed. Histopathological examination showed non-perforating gangrenous appendicitis. He required DIC therapy for 2 days postoperatively. He was discharged on postoperative day 9, and remained in good health 1 month after surgery. DISCUSSION: There is no absolute index of conversion to surgery with an antibiotics-first strategy of appendicitis treatment. Judging the limit of conservative treatment and determining the best moment to perform surgery is a critically important matter for patients with acute appendicitis.

conclusionsThe incidence of conservative treatment preceding an antibiotics-first strategy for acute appendicitis is increasing. However, it is thought that appendectomy should be performed when acute appendicitis is complicated with septic DIC, even if it is a non-perforating appendicitis in which improvement with conservative treatment is anticipated.

Indexed as

Disseminated intravascular coagulation (DIC)Non-perforating appendicitisSepticUncomplicated appendicitis

Identifiers

PMID30716702
PMCPMC6360458
OpenAlexW2913924664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.