Evidence map›Paper›PMID 30716669›Full record

Trial reportGait & posture2019

Postural sway, falls, and self-reported neuropathy in aging female cancer survivors.

Peter C Fino, Fay B Horak, Mahmoud El-Gohary, Carolyn Guidarelli, Mary E Medysky, Sarah J Nagle, Kerri M Winters-Stone

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Gait & posture, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Article
  7. Observational
  8. Incidence and associated factors of falls in patients with chemotherapy-induced peripheral neuropathy: a scoping review and evidence mapping.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  9. Article
  10. Survivorship Issues in Older Adults with Breast Cancer.Current breast cancer reports · 2025
    Article
  11. Observational
  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Peter C FinoDepartment of Neurology, Oregon Health & Science University, United States; Department of Health, Kinesiology, and Recreation, University of Utah, United States. Electronic address: peter.fino@utah.edu.
Fay B HorakDepartment of Neurology, Oregon Health & Science University, United States.
Mahmoud El-GoharyAPDM, Inc., United States.
Carolyn GuidarelliSchool of Nursing, Oregon Health & Science University, United States.
Mary E MedyskySchool of Nursing, Oregon Health & Science University, United States.
Sarah J NagleKnight Cancer Institute, Oregon Health & Science University, United States.
Kerri M Winters-StoneSchool of Nursing, Oregon Health & Science University, United States; Knight Cancer Institute, Oregon Health & Science University, United States.
Oregon Health & Science University · USAPDM (United States) · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Preventing falls after cancer: Tai chi vs. strength trainingR01CA163474 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WINTERS-STONE, KERRI M · 2012 to 2016
$3.0M
Intramural NIH HHS Z99 CA999999NCATS NIH HHS UL1 TR002369NCI NIH HHS HHSN261201600067CNCI NIH HHS R01 CA163474
6 · The paper itself

Abstract

backgroundFalls are a major public health concern in older adults, and the proportion of older adults that has been diagnosed with cancer is growing. Yet, while falls, peripheral neuropathy, and postural instability are more common in aging cancer survivors, it is unclear how these factors interact. RESEARCH QUESTION: Our objective was to examine how components of sway related to self-reported neuropathy and falls.

methodsPostural sway during static stance was recorded with an inertial sensor (APDM Opal), placed on the lumbar spine region in 434 older female cancer survivors (mean age 63) and 49 healthy older female control subjects (mean age 63). Measures of sway were resolved into principal components that were compared between women with and women without self-reported falls in the previous 6 months and between those with and without self-reported symptoms of peripheral neuropathy.

resultsCancer survivors had worse sway than healthy control subjects in components related to sway magnitude and mediolateral frequency of sway, but no difference in the component related to resultant / AP sway jerk and frequency. Cancer survivors who reported neuropathy were more likely to have higher resultant / AP sway frequencies and jerk than asymptomatic survivors, while survivors who reported a fall were more likely to have lower frequencies of mediolateral sway than non-fallers. Falls were more strongly associated with mediolateral sway in survivors with more severe neuropathy; whereas falls were more strongly associated with resultant / AP sway frequency in survivors with less severe neuropathy SIGNIFICANCE: Postural stability, falls, and neuropathy have complex interactions that can vary across components of postural sway. While the frequency of mediolateral sway was associated with falls across our entire cohort, neuropathy influenced the associations between specific characteristics of sway and falls, which may have implications for fall prevention interventions.

Indexed as

Cancer SurvivorsSelf ReportAccidental FallsAgedAgingFemaleHumansMiddle AgedNeoplasmsPeripheral Nervous System DiseasesPostural BalanceBalanceChemotherapyMediolateralPostural stability

Identifiers

PMID30716669
PMCPMC6579642
OpenAlexW2910208936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.