Evidence map›Paper›PMID 30716271›Full record

ReviewJournal of the American Chemical Society2019

Oligosaccharide Synthesis and Translational Innovation.

Larissa Krasnova, Chi-Huey Wong

Abstract readReview
In one paragraph

Review in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 200 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Chemical Synthesis of Complex Carbohydrates.Handbook of experimental pharmacology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Dynamic Kinetic Stereoselective Glycosylation via RhAngewandte Chemie (International ed. in English) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. VaporSPOT: Parallel Synthesis of Oligosaccharides on Membranes.Journal of the American Chemical Society · 2022
    Article
  20. Automating Glycan Assembly in Solution.ACS central science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Larissa KrasnovaDepartment of Chemistry , The Scripps Research Institute , 10550 N. Torrey Pines Road , La Jolla , California 92037 , United States.ORCID 0000-0002-1657-4311
Chi-Huey WongDepartment of Chemistry , The Scripps Research Institute , 10550 N. Torrey Pines Road , La Jolla , California 92037 , United States.ORCID 0000-0002-9961-7865
Scripps Research Institute · US

Funding

Carbohydrate-based Antiinfective AgentsR01AI072155 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI WONG, CHI-HUEY · 2007 to 2014
$3.7M
Targeting Influenza A Virus by a Carbohydrate-inspired StrategyR01AI130227 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI CHI-HUEY WONG · 2019 to 2026
$3.3M
NIAID NIH HHS R01 AI072155NIAID NIH HHS R01 AI130227
6 · The paper itself

Abstract

The translation of biological glycosylation in humans to the clinical applications involves systematic studies using homogeneous samples of oligosaccharides and glycoconjugates, which could be accessed by chemical, enzymatic or other biological methods. However, the structural complexity and wide-range variations of glycans and their conjugates represent a major challenge in the synthesis of this class of biomolecules. To help navigate within many methods of oligosaccharide synthesis, this Perspective offers a critical assessment of the most promising synthetic strategies with an eye on the therapeutically relevant targets.

Indexed as

GlycosylationHumansMolecular StructureOligosaccharidesOligosaccharides

Identifiers

PMID30716271
PMCPMC6538563
OpenAlexW2913478876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.