Evidence map›Paper›PMID 30716032›Full record

ArticleIEEE transactions on medical imaging2019

Robust Non-Rigid Motion Compensation of Free-Breathing Myocardial Perfusion MRI Data.

Cian M Scannell, Adriana D M Villa, Jack Lee, Marcel Breeuwer, Amedeo Chiribiri

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Society for cardiovascular magnetic resonance expert consensus statement on quantitative myocardial perfusion cardiovascular magnetic resonance imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
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  17. Deep-Learning-Based Preprocessing for Quantitative Myocardial Perfusion MRI.Journal of magnetic resonance imaging : JMRI · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cian M Scannell
Adriana D M Villa
Jack Lee
Marcel Breeuwer
Amedeo Chiribiri

Funding

Department of HealthWellcome TrustWellcome Trust 088641Wellcome Trust 203148/Z/16/Z
6 · The paper itself

Abstract

Kinetic parameter values, such as myocardial perfusion, can be quantified from dynamic contrast-enhanced magnetic resonance imaging data using tracer-kinetic modeling. However, respiratory motion affects the accuracy of this process. Motion compensation of the image series is difficult due to the rapid local signal enhancement caused by the passing of the gadolinium-based contrast agent. This contrast enhancement invalidates the assumptions of the (global) cost functions traditionally used in intensity-based registrations. The algorithms are unable to distinguish whether the differences in signal intensity between frames are caused by the spatial motion artifacts or the local contrast enhancement. In order to address this problem, a fully automated motion compensation scheme is proposed, which consists of two stages. The first of which uses robust principal component analysis (PCA) to separate the local signal enhancement from the baseline signal, before a refinement stage which uses the traditional PCA to construct a synthetic reference series that is free from motion but preserves the signal enhancement. Validation is performed on 18 subjects acquired in free-breathing and 5 clinical subjects acquired with a breath-hold. The validation assesses the visual quality, the temporal smoothness of tissue curves, and the clinically relevant quantitative perfusion values. The expert observers score the visual quality increased by a mean of 1.58/5 after motion compensation and improvement over the previously published methods. The proposed motion compensation scheme also leads to the improved quantitative performance of motion compensated free-breathing image series [30% reduction in the coefficient of variation across quantitative perfusion maps and 53% reduction in temporal variations (p < 0.001)].

Indexed as

RespirationAlgorithmsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementMyocardial Perfusion Imaging

Identifiers

PMID30716032
PMCPMC6699991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.