Evidence map›Paper›PMID 30715779›Full record

ArticleDevelopmental science2019

Mechanisms linking height to early child development among infants and preschoolers in rural India.

Maureen M Black, Doris P Yimgang, Kristen M Hurley, Kimberly B Harding, Sylvia Fernandez-Rao, Nagalla Balakrishna, Kankipati V Radhakrishna, Gregory A Reinhart, Krishnapillai Madhavan Nair

Open access · greenAbstract read
In one paragraph

Article in Developmental science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Maureen M BlackDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD.
Doris P YimgangDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
Kristen M HurleyCenter for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Kimberly B HardingNutrition International, Ottawa, ON, Canada.
Sylvia Fernandez-RaoNational Institute of Nutrition, Hyderabad, Telangana, India.
Nagalla BalakrishnaNational Institute of Nutrition, Hyderabad, Telangana, India.
Kankipati V RadhakrishnaNational Institute of Nutrition, Hyderabad, Telangana, India.
Gregory A ReinhartMathile Institute for the Advancement of Human Nutrition, Dayton, OH.
Krishnapillai Madhavan NairNational Institute of Nutrition, Hyderabad, Telangana, India.
National Institute of Nutrition · INUniversity of Maryland, Baltimore · USJohns Hopkins University · USMathile Institute For The Advancement of Human Nutrition · USNutrition International · CA

Funding

EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Association between iron deficiency with or without anemia and child development among infants: cross-sectional and longitudinal analysesF31HD095615 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI YIMGANG NGANDJOUONG, DORIS · 2018 to 2019
$46k
NICHD NIH HHS F31 HD095615NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

Stunting has been negatively associated with children's development. We examined the range of height by testing hypotheses: (a) height is positively associated with children's development, with associations moderated by inflammation and (b) home environments characterized by nurturance and early learning opportunities is positively associated with children's development over time and attenuate associations with height. Data included 513 infants (mean age 8.6 months) and 316 preschoolers (mean age 36.6 months) in rural India from a randomized controlled trial of multiple micronutrient powders (MNPs). Measures included height (height-for-age z-scores based on WHO standards), inflammation (C-reactive protein concentration >5 mg/L), nurturance (HOME Inventory), child development (Mullens Scales of Early Learning), and inhibitory control (preschoolers). Linear mixed effects models accounting for repeated measures, clustering, and confounders were used to assess associations between height and child development over time (infants: enrollment, 6 and 12 months; preschoolers: enrollment and 8 months). Moderating effects of inflammation and nurturance were tested with interaction terms. Among infants and preschoolers, height and nurturance were positively associated with all domains of child development over time, with the exception of inhibitory control. Among preschoolers, in the presence of inflammation, height was not associated with child development. Among infants, but not preschoolers, a nurturant home environment attenuated significant associations between height with fine motor and receptive language development. The mechanisms associated with children's development over time are multifactorial and include direct and indirect associations among nutrition, health, and the home environment, as supported by the Nurturing Care Framework.

Indexed as

Body HeightChildChild DevelopmentChild, PreschoolFemaleHumansIndiaInfantInflammationLearningMaleParentingRandomized Controlled Trials as TopicRural Population1,000 dayschild developmentglobalheightHOMEinfant developmentinflammationpreschool developmentstunting

Identifiers

PMID30715779
PMCPMC7428854
OpenAlexW2911593404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.