Evidence map›Paper›PMID 30715752›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2019

External Bone Size Is a Key Determinant of Strength-Decline Trajectories of Aging Male Radii.

Erin Mr Bigelow, Daniella M Patton, Ferrous S Ward, Antonio Ciarelli, Michael Casden, Andrea Clark, Robert W Goulet, Michael D Morris, Stephen H Schlecht, Gurjit S Mandair and 3 more

Abstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Femoral neck width is associated with unique trajectories of age-related hip structural changes and fracture risk within populations of adult women and men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
  3. Article
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  5. Review
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  12. Article
  13. Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  14. Axial Transmission: Techniques, Devices and Clinical Results.Advances in experimental medicine and biology · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Erin Mr BigelowDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Daniella M PattonDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Ferrous S WardDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Antonio CiarelliDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Michael CasdenSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Andrea ClarkDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Robert W GouletDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Michael D MorrisCollege of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI, USA.
Stephen H SchlechtMechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Gurjit S MandairBiological and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Todd L BredbennerDepartment of Mechanical and Aerospace Engineering, University of Colorado-Colorado Springs, Colorado Springs, CO, USA.
David H KohnBiomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Karl J JepsenDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
THE ROLE OF BONE TRAIT COVARIATION IN VERTEBRAL FRACTURE RESISTANCER01AR064244 · NIAMS · UNIVERSITY OF COLORADO · PI BREDBENNER, TODD L · 2013 to 2017
$2.7M
Bone Robustness as a Biomarker of Skeletal Aging and FragilityR01AR065424 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JEPSEN, KARL J · 2014 to 2018
$2.4M
Changes in Periosteal and Endocortical Width Across the Menopausal TransitionR01AR068452 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JEPSEN, KARL J · 2018 to 2022
$2.2M
Natural Variation in the Growth and Development of the ACL ComplexR00AR070903 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI SCHLECHT, STEPHEN · 2019 to 2021
$739k
Natural Variation in the Growth and Development of the ACL ComplexK99AR070903 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLECHT, STEPHEN · 2017 to 2018
$184k
NIAMS NIH HHS K99 AR070903NIAMS NIH HHS P30 AR069620NIAMS NIH HHS R00 AR070903NIAMS NIH HHS R01 AR064244NIAMS NIH HHS R01 AR065424NIAMS NIH HHS R01 AR068452NIDCR NIH HHS T32 DE007057NIH HHS AR068452NIH HHS AR069620NIH HHS DHK: T32DE007057NIH HHS KJJ AR065424NIH HHS SHS: AR070903NIH HHS TLB: AR064244
6 · The paper itself

Abstract

Given prior work showing associations between remodeling and external bone size, we tested the hypothesis that wide bones would show a greater negative correlation between whole-bone strength and age compared with narrow bones. Cadaveric male radii (n = 37 pairs, 18 to 89 years old) were evaluated biomechanically, and samples were sorted into narrow and wide subgroups using height-adjusted robustness (total area/bone length). Strength was 54% greater (p < 0.0001) in wide compared with narrow radii for young adults (<40 years old). However, the greater strength of young-adult wide radii was not observed for older wide radii, as the wide (R

Indexed as

AgingBone DensityRadiusAdolescentAdultAgedAged, 80 and overHumansMaleMiddle AgedOrgan SizeAGINGBIOMECHANICAL MECHANISMSBIOMECHANICSBONEMALEPERIOSTEAL EXPANSIONRADIISTRENGTH

Identifiers

PMID30715752
PMCPMC6536328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.