Evidence map›Paper›PMID 30715575›Full record

SynthesisInternational urogynecology journal2019

Heterogeneity of cost estimates in health economic evaluation research. A systematic review of stress urinary incontinence studies.

Sandra Zwolsman, Arnoud Kastelein, Joost Daams, Jan-Paul Roovers, B C Opmeer, WOMEN-UP Consortium: http://www.women-up.eu/consortium/

Abstract readSystematic Review
In one paragraph

Synthesis in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Single-incision sling operations for urinary incontinence in women.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Cost-Effectiveness of Perinatal Depression Screening: A Scoping Review.Applied health economics and health policy · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra ZwolsmanDepartment of Gynaecology and Obstetrics, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands. s.e.zwolsman@amc.uva.nl.ORCID 0000-0002-5863-5629
Arnoud KasteleinDepartment of Gynaecology and Obstetrics, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.
Joost DaamsMedical Library, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.
Jan-Paul RooversDepartment of Gynaecology and Obstetrics, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.
B C OpmeerClinical Research Unit, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.
WOMEN-UP Consortium: http://www.women-up.eu/consortium/

Funding

Horizon 2020 643535
6 · The paper itself

Abstract

introduction and hypothesisThere is increased demand for an international overview of cost estimates and insight into the variation affecting these estimates. Understanding of these costs is useful for cost-effectiveness analysis (CEA) research into new treatment modalities and for clinical guideline development.

methodsA systematic search was conducted in Ovid MEDLINE & other non-indexed materials and Ovid Embase for articles published between 1995 and 2017. The National Health Service Economic Evaluation Database (NHS-EED) filter and the McMaster sensitive therapy filter were combined with a bespoke search strategy for stress urinary incontinence (SUI). We extracted unit cost estimates, assessed variability and methodology, and determined transferability.

resultsWe included 37 studies in this review. Four hundred and eighty-two cost estimates from 13 countries worldwide were extracted. Descriptive analysis shows that hospital stay in gynecology ranged between €82 and €1,292 per day. Costs of gynecological consultation range from €30 in France to €158 in Sweden. In the UK, costs are estimated at €228 per hour. Costs of a tension-free vaginal tape (TVT) device range from €431 in Finland to €994 in Canada. TVT surgery per minute costs €25 in France and €82 in Sweden. Total costs of TVT range from €1,224 in Ireland to €5,809 for inpatient care in France. Variation was explored.

conclusionsHeterogeneity was observed in cost estimates for all units at all levels of health care. CEAs of SUI interventions cannot be interpreted without bias when the base of these analyses-namely costs-cannot be compared and generalized.

Indexed as

Health Services ResearchCost-Benefit AnalysisFemaleGynecologyHealth Care CostsHospital CostsHumansSuburethral SlingsUrinary Incontinence, StressHealth care costsHealth economic evaluation researchHealth technologyMultinationalStandardized unit costsTransferability

Identifiers

PMID30715575
PMCPMC6586692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.