ArticleSocial cognitive and affective neuroscience2019
Neural correlates of social well-being: gray matter density in the orbitofrontal cortex predicts social well-being in emerging adulthood.
Article in Social cognitive and affective neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gray matter structures associated with neuroticism: A meta-analysis of whole-brain voxel-based morphometry studies.Human brain mapping · 2021Pooled it
- Structural Brain Correlates of Multidomain Resilience Among Youth Exposed to Neighborhood Disadvantage.Biological psychiatry global open science · 2025Article
- If you're happy and you know it: neural correlates of self-evaluated psychological health and well-being.Social cognitive and affective neuroscience · 2023Article
- Emotional intelligence mediates the protective role of the orbitofrontal cortex spontaneous activity measured by fALFF against depressive and anxious symptoms in late adolescence.European child & adolescent psychiatry · 2023Article
- Well-being is associated with cortical thickness network topology of human brain.Behavioral and brain functions : BBF · 2023Article
- Good personality and social well-being: The roles of orientation to happiness.Frontiers in public health · 2023Article
- Common and distinct neural substrates of the compassionate and uncompassionate self-responding dimensions of self-compassion.Brain imaging and behavior · 2022Article
- Brain conditions mediate the association between aging and happiness.Scientific reports · 2022Article
- Well-Being Is Associated With Local to Remote Cortical Connectivity.Frontiers in behavioral neuroscience · 2022Article
- Psychometric validation of the Persian version of the Emotional Style Questionnaire.Current psychology (New Brunswick, N.J.) · 2022Article
- Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters.Scientific reports · 2021Article
- Piecing together the orbitofrontal puzzle.Behavioral neuroscience · 2021Article
- Neurostructural correlates of hope: dispositional hope mediates the impact of the SMA gray matter volume on subjective well-being in late adolescence.Social cognitive and affective neuroscience · 2020Article
- Neurostructural correlates of optimism: Gray matter density in the putamen predicts dispositional optimism in late adolescence.Human brain mapping · 2020Article
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Authors and funding
6 authors.
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Abstract
Social well-being reflects the perception of one's social functioning, which plays an important role in physical and psychological health. However, the exact neuroanatomical substrate for social well-being remains unclear. To address the issue, we employed the voxel-based morphometry method to probe the neuroanatomical basis of individual variation in social well-being in young healthy adults (n = 136). The results revealed a significant negative association between social well-being and regional gray matter density (rGMD) in an anatomical cluster that mainly includes the left orbitofrontal cortex (OFC) that has been involved in emotion regulation and social cognition. Furthermore, a balanced 4-fold cross-validation using the machine learning approach revealed that rGMD in the left OFC could be reliably related to social well-being. More importantly, the multiple mediation analysis revealed that neuroticism and dispositional forgiveness independently mediated the association between rGMD in the left OFC and social well-being. In addition, all these results remained stable when subjective socioeconomic status was controlled. Together, our results provide the initial evidence that the OFC is a neuroanatomical substrate for social well-being and demonstrate that the OFC is a crucial neural site linking neuroticism and dispositional forgiveness to social well-being.
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