ArticleMolecular biology and evolution2019
An Insect Counteradaptation against Host Plant Defenses Evolved through Concerted Neofunctionalization.
Article in Molecular biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 67 citations in OpenAlex.
- Unveiling Plant Metabolic Diversity: Integrating Metabolomics with Multi-Omics Approaches for Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Defense Responses of Cucumber and Cowpea toPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Characterization of Four Gastropod Species Ionotropic Receptors Reveals Diet-Linked Evolutionary Patterns of Functional Divergence.Animals : an open access journal from MDPI · 2026Article
- Article
- Multiple glutathione-S-transferases detoxify diverse glucosinolate-based defenses of Brassicales plants in a generalist lepidopteran herbivore (Spodoptera littoralis).Communications biology · 2025Article
- Ectopic Gene Conversion Causing Quantitative Trait Variation.Molecular biology and evolution · 2025Article
- Article
- Can genomic signatures guide the selection of host-specific agents for weed biological control?Evolutionary applications · 2024Article
- Metabolism of plant-derived toxins from its insect host increases the success of the entomopathogenic fungus Beauveria bassiana.The ISME journal · 2023Article
- New Insights into theJournal of agricultural and food chemistry · 2023Review
- Article
- Article
- Antibody-Based Methods Reveal the Protein Expression Properties of Glucosinolate Sulfatase 1 and 2 in Plutella xylostella.Journal of insect science (Online) · 2022Article
- Family dinner: Transcriptional plasticity of five Noctuidae (Lepidoptera) feeding on three host plant species.Ecology and evolution · 2022Article
- Pesticide resistance in arthropods: Ecology matters too.Ecology letters · 2022Article
- Evolution of Olfactory Receptors Tuned to Mustard Oils in Herbivorous Drosophilidae.Molecular biology and evolution · 2022Article
- Expanding the Menu: Are Polyphagy and Gene Family Expansions Linked across Lepidoptera?Genome biology and evolution · 2022Article
- An inducible gene from glycoside hydrolase one family ofFrontiers in physiology · 2022Article
- Horizontal Gene Transfer and Gene Duplication of β-Fructofuranosidase Confer Lepidopteran Insects Metabolic Benefits.Molecular biology and evolution · 2021Article
- Insect egg-killing: a new front on the evolutionary arms-race between brassicaceous plants and pierid butterflies.The New phytologist · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antagonistic chemical interactions between herbivorous insects and their host plants are often thought to coevolve in a stepwise process, with an evolutionary innovation on one side being countered by a corresponding advance on the other. Glucosinolate sulfatase (GSS) enzyme activity is essential for the Diamondback moth, Plutella xylostella, to overcome a highly diversified secondary metabolite-based host defense system in the Brassicales. GSS genes are located in an ancient cluster of arylsulfataselike genes, but the exact roles of gene copies and their evolutionary trajectories are unknown. Here, we combine a functional investigation of duplicated insect arylsulfatases with an analysis of associated nucleotide substitution patterns. We show that the Diamondback moth genome encodes three GSSs with distinct substrate spectra and distinct expression patterns in response to glucosinolates. Contrary to our expectations, early functional diversification of gene copies was not indicative of a coevolutionary arms race between host and herbivore. Instead, both copies of a duplicated arylsulfatase gene evolved concertedly in the context of an insect host shift to acquire novel detoxifying functions under positive selection, a pattern of duplicate gene retention that we call "concerted neofunctionalization."
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.