ArticleGigaScience2019
The genomic basis for colonizing the freezing Southern Ocean revealed by Antarctic toothfish and Patagonian robalo genomes.
Article in GigaScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 62 citations in OpenAlex.
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- A new phased assembly of the Antarctic spiny plunderfish provides novel insights into the evolution of the notothenioid radiation.bioRxiv : the preprint server for biology · 2026Article
- A Field-Friendly, Non-Toxic Fixative for Integrated Morphological and Molecular Research in Non-Model Invertebrates.Ecology and evolution · 2026Article
- Sex Differentiation and Long-Distance Gene Flow in the Elusive Antarctic FishEcology and evolution · 2025Article
- Genomic Signals of Local Adaptation Associated With Environmental Variables inEcology and evolution · 2025Article
- Multiple Pathways of Visual Adaptations for Water Column Usage in an Antarctic Adaptive Radiation.Ecology and evolution · 2025Article
- Advances in biotechnology and breeding innovations in China's marine aquaculture.Advanced biotechnology · 2024Review
- Metabolomic-based analysis reveals bile acid-mediated ovarian failure induced by low temperature in zebrafish.Zoological research · 2024Article
- Identification of two miRNAs regulating cardiomyocyte proliferation in an Antarctic icefish.iScience · 2024Article
- De novo assembly and annotation of the Patagonian toothfish (Dissostichus eleginoides) genome.BMC genomics · 2024Article
- Chromosome-level genome assembly and annotation of the Antarctica whitefin plunderfish Pogonophryne albipinna.Scientific data · 2023Article
- Cold-Driven Hemoglobin Evolution in Antarctic Notothenioid Fishes Prior to Hemoglobin Gene Loss in White-Blooded Icefishes.Molecular biology and evolution · 2023Article
- Genomics of cold adaptations in the Antarctic notothenioid fish radiation.Nature communications · 2023Article
- Article
- The adaptive evolution of Leuciscus waleckii in Lake Dali Nur and convergent evolution of Cypriniformes fishes inhabiting extremely alkaline environments.Genome biology and evolution · 2023Article
- Positive and Relaxed Selective Pressures Have Both Strongly Influenced the Evolution of Cryonotothenioid Fishes during Their Radiation in the Freezing Southern Ocean.Genome biology and evolution · 2023Article
- Article
- Population genomics of an icefish reveals mechanisms of glacier-driven adaptive radiation in Antarctic notothenioids.BMC biology · 2022Article
- Neutral and adaptive loci reveal fine-scale population structure inEcology and evolution · 2022Article
- Whole-Genome Survey and Microsatellite Marker Detection of Antarctic Crocodile Icefish,Animals : an open access journal from MDPI · 2022Article
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Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Southern Ocean is the coldest ocean on Earth but a hot spot of evolution. The bottom-dwelling Eocene ancestor of Antarctic notothenioid fishes survived polar marine glaciation and underwent adaptive radiation, forming >120 species that fill all water column niches today. Genome-wide changes enabling physiological adaptations and the rapid expansion of the Antarctic notothenioids remain poorly understood.
resultsWe sequenced and compared 2 notothenioid genomes-the cold-adapted and neutrally buoyant Antarctic toothfish Dissostichus mawsoni and the basal Patagonian robalo Eleginops maclovinus, representing the temperate ancestor. We detected >200 protein gene families that had expanded and thousands of genes that had evolved faster in the toothfish, with diverse cold-relevant functions including stress response, lipid metabolism, protein homeostasis, and freeze resistance. Besides antifreeze glycoprotein, an eggshell protein had functionally diversified to aid in cellular freezing resistance. Genomic and transcriptomic comparisons revealed proliferation of selcys-transfer RNA genes and broad transcriptional upregulation across anti-oxidative selenoproteins, signifying their prominent role in mitigating oxidative stress in the oxygen-rich Southern Ocean. We found expansion of transposable elements, temporally correlated to Antarctic notothenioid diversification. Additionally, the toothfish exhibited remarkable shifts in genetic programs towards enhanced fat cell differentiation and lipid storage, and promotion of chondrogenesis while inhibiting osteogenesis in bone development, collectively contributing to the achievement of neutral buoyancy and pelagicism.
conclusionsOur study revealed a comprehensive landscape of evolutionary changes essential for Antarctic notothenioid cold adaptation and ecological expansion. The 2 genomes are valuable resources for further exploration of mechanisms underlying the spectacular notothenioid radiation in the coldest marine environment.
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