Evidence map›Paper›PMID 30714967›Full record

ArticleJournal of neuromuscular diseases

Exploration of New Contrasts, Targets, and MR Imaging and Spectroscopy Techniques for Neuromuscular Disease - A Workshop Report of Working Group 3 of the Biomedicine and Molecular Biosciences COST Action BM1304 MYO-MRI.

Gustav J Strijkers, Ericky C A Araujo, Noura Azzabou, David Bendahan, Andrew Blamire, Jedrek Burakiewicz, Pierre G Carlier, Bruce Damon, Xeni Deligianni, Martijn Froeling and 19 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Journal of neuromuscular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Compositional and Functional MRI of Skeletal Muscle: A Review.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Journal of orthopaedic translation · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Effects of muscle damage onNMR in biomedicine · 2022
    Article
  14. Article
  15. QuantitativeJournal of neurology · 2021
    Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 19 institutions in 6 countries.

Gustav J StrijkersAmsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Ericky C A AraujoNMR Laboratory, Neuromuscular Investigation Center, Institute of Myology & NMR Laboratory, CEA/DRF/IBFJ/MIRCen, Paris, France.
Noura AzzabouNMR Laboratory, Neuromuscular Investigation Center, Institute of Myology & NMR Laboratory, CEA/DRF/IBFJ/MIRCen, Paris, France.
David BendahanAix Marseille University, Marseille, France.
Andrew BlamireInstitute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK.
Jedrek BurakiewiczDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Pierre G CarlierNMR Laboratory, Neuromuscular Investigation Center, Institute of Myology & NMR Laboratory, CEA/DRF/IBFJ/MIRCen, Paris, France.
Bruce DamonVanderbilt University Medical Center, Nashville, USA.
Xeni DeligianniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland & Department of Biomedical Engineering, University of Basel, Basel, Switzerland.
Martijn FroelingUniversity Medical Center Utrecht, Utrecht, the Netherlands.
Arend HeerschapRadboud University Medical Center, Nijmegen, the Netherlands.
Kieren G HollingsworthInstitute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK.
Melissa T HooijmansAmsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Dimitrios C KarampinosTechnical University of Munich, Munich, Germany.
George LoudosBioEimmision Technology Solutions, Athens, Greece.
Guillaume MadelinNew York University School of Medicine, New York, USA.
Benjamin MartyNMR Laboratory, Neuromuscular Investigation Center, Institute of Myology & NMR Laboratory, CEA/DRF/IBFJ/MIRCen, Paris, France.
Armin M NagelInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany & Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Aart J NederveenAmsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Jules L NelissenAmsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Francesco SantiniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland & Department of Biomedical Engineering, University of Basel, Basel, Switzerland.
Olivier ScheideggerDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Fritz SchickUniversity of Tübingen, Section on Experimental Radiology, Tübingen, Germany.
Christopher SinclairUCL Institute of Neurology, London, UK.
Ralph SinkusKing's College London, London, UK.
Paulo L de SousaUniversité de Strasbourg, Strasbourg, France.
Volker StraubInstitute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK.
Glenn WalterUniversity of Florida, Gainesville, USA.
Hermien E KanDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Amsterdam University Medical Centers · NLCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRNewcastle University · GBLeiden University Medical Center · NLUniversity of Basel · CHAix-Marseille Université · FRGerman Cancer Research Center · DEKing's College London · GBMission Bio (United States) · USRadboud University Nijmegen · NLTechnical University of Munich · DEUniversité de Strasbourg · FRUniversity College London · GBUniversity Medical Center Utrecht · NLUniversity of Bern · CHUniversity of Florida · USUniversity of Tübingen · DEUniversity School · USVanderbilt University Medical Center · US

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3M
Medical Research Council G1100160NIAMS NIH HHS U54 AR052646NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Neuromuscular diseases are characterized by progressive muscle degeneration and muscle weakness resulting in functional disabilities. While each of these diseases is individually rare, they are common as a group, and a large majority lacks effective treatment with fully market approved drugs. Magnetic resonance imaging and spectroscopy techniques (MRI and MRS) are showing increasing promise as an outcome measure in clinical trials for these diseases. In 2013, the European Union funded the COST (co-operation in science and technology) action BM1304 called MYO-MRI (www.myo-mri.eu), with the overall aim to advance novel MRI and MRS techniques for both diagnosis and quantitative monitoring of neuromuscular diseases through sharing of expertise and data, joint development of protocols, opportunities for young researchers and creation of an online atlas of muscle MRI and MRS. In this report, the topics that were discussed in the framework of working group 3, which had the objective to: Explore new contrasts, new targets and new imaging techniques for NMD are described. The report is written by the scientists who attended the meetings and presented their data. An overview is given on the different contrasts that MRI can generate and their application, clinical needs and desired readouts, and emerging methods.

Indexed as

Contrast MediaAnimalsDog DiseasesDogsEuropean UnionHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMusclesNeuromuscular DiseasesContrast MediabiomarkerMRIMRSmusclemyo-mriNeuromuscular diseaseoutcome measure

Identifiers

PMID30714967
PMCPMC6398566
OpenAlexW2913925905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.