Evidence map›Paper›PMID 30714905›Full record

ArticleeLife2019

Retinal direction selectivity in the absence of asymmetric starburst amacrine cell responses.

Laura Hanson, Santhosh Sethuramanujam, Geoff deRosenroll, Varsha Jain, Gautam B Awatramani

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

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  14. Temporal vision: measures, mechanisms and meaning.The Journal of experimental biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura Hanson *Department of Biology, University of Victoria, Victoria, Canada.ORCID 0000-0002-8737-9513
Santhosh Sethuramanujam *Department of Biology, University of Victoria, Victoria, Canada.ORCID 0000-0001-6199-1221
Geoff deRosenrollDepartment of Biology, University of Victoria, Victoria, Canada.ORCID 0000-0002-5431-2814
Varsha JainDepartment of Biology, University of Victoria, Victoria, Canada.ORCID 0000-0002-1620-4177
Gautam B AwatramaniDepartment of Biology, University of Victoria, Victoria, Canada.ORCID 0000-0002-0610-5271
University of Victoria · CA

Funding

CIHR 159444
6 · The paper itself

Abstract

In the mammalian retina, direction-selectivity is thought to originate in the dendrites of GABAergic/cholinergic starburst amacrine cells, where it is first observed. However, here we demonstrate that direction selectivity in downstream ganglion cells remains remarkably unaffected when starburst dendrites are rendered non-directional, using a novel strategy combining a conditional GABA

Indexed as

OptogeneticsAcetylcholineAmacrine CellsAnimalsDendritesMiceMice, KnockoutReceptors, GABA-ARetinaRetinal Ganglion CellsSynapsesVisual PathwaysAcetylcholineReceptors, GABA-Aco-transmissiondirection selectivityE/I balanceganglion cellsmouseneuroscienceretinal circuitrystarburst amacrine cells

Identifiers

PMID30714905
PMCPMC6377229
OpenAlexW2949394297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.