Evidence map›Paper›PMID 30714501›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2019

Thrombus perviousness is not associated with first-pass revascularization using stent retrievers.

Jun-Soo Byun, Patrick Nicholson, Christopher A Hilditch, Anderson Chun On Tsang, Vitor Mendes Pereira, Timo Krings, Yibin Fang, Waleed Brinjikji

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  9. Magnetic resonance imaging quantitative T2* mapping to predict the red blood cell content of in vivo thrombi retrieved from patients with large vessel occlusions in acute ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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  10. Clot imaging characteristics predict first pass effect of aspiration-first approach to thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jun-Soo ByunJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Patrick NicholsonJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Christopher A HilditchJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Anderson Chun On TsangJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.ORCID https://orcid.org/0000-0003-2758-3253
Vitor Mendes PereiraJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Timo KringsJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Yibin FangJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.
Waleed BrinjikjiJoint Department of Medical Imaging, Toronto Western Hospital, Toronto, Canada.ORCID https://orcid.org/0000-0001-5271-5524
Toronto Western Hospital · CA

Funding

Impact of Clot Histological and Physical Properties on Revascularization Strategies in Acute Ischaemic Stroke - Administrative SupplementR01NS105853 · NINDS · MAYO CLINIC ROCHESTER · PI BRINJIKJI, WALEED · 2018 to 2022
$2.0M
NINDS NIH HHS R01 NS105853
6 · The paper itself

Abstract

background and purposeRecent studies suggest that thrombus imaging characteristics such as Hounsfield unit (HU) and perviousness assessed on noncontrast computed tomography (NCCT) and CT angiography (CTA) can predict successful recanalization. We assessed whether these thrombus imaging characteristics could predict successful first-pass recanalization.

methodsWe retrospectively reviewed cases of mechanical thrombectomy over a three-year period in which patients received a multiphase CTA and were treated with a stent retriever on first pass. Thrombus attenuation, thrombus enhancement on arterial- and delayed-phase CTA and percentage washout were calculated and their association with first-pass recanalization, successful recanalization and distal embolic complications was studied.

resultsFifty-two mechanical thrombectomy patients were included. First-pass recanalization was achieved in 59.6% and complete revascularization (Thrombolysis in Cerebral Infarction scale 2b/3) was achieved in 84.6%. There was no correlation between first-pass recanalization with thrombus density on NCCT ( p = 0.94), percentage enhancement on arterial ( p = 0.61) and delayed-phase CTA ( p = 0.23) or thrombus length ( p = 0.16). There was no correlation between number of passes and either thrombus density on NCCT ( p = 0.91) or percentage enhancement on arterial- ( p = 0.79) and delayed-phase ( p = 0.14) CTA or thrombus length ( p = 0.34). Clot length was significantly higher in patients with distal embolic complications than in those without (18.5 ± 7.9 vs 11.4 ± 6.6 mm, p = 0.005).

conclusionsOur data suggest that thrombus imaging characteristics on multiphase CTA cannot predict first-pass recanalization or successful revascularization in acute ischemic stroke patients treated with stent retrievers. Longer clot length was associated with higher risk of distal embolic complications.

Indexed as

AgedAged, 80 and overCerebral AngiographyCerebral RevascularizationFemaleHumansIntracranial EmbolismIntracranial ThrombosisMaleMiddle AgedPredictive Value of TestsRetrospective StudiesStentsStrokeThrombectomyTomography, X-Ray ComputedCTAperviousnessstrokethrombectomythrombus

Identifiers

PMID30714501
PMCPMC6547211
OpenAlexW2913702495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.