Evidence map›Paper›PMID 30714446›Full record

ArticleLeukemia & lymphoma2019

PET-derived tumor metrics predict DLBCL response and progression-free survival.

Prioty Islam, Jordan Goldstein, Christopher R Flowers

Open access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Evaluating ΔMTV%, ΔDDiscover oncology · 2025
    Article
  7. Article
  8. Prognostic value ofQuantitative imaging in medicine and surgery · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Interobserver Agreement on Automated Metabolic Tumor Volume Measurements of Deauville Score 4 and 5 Lesions at InterimJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  16. Article
  17. Predictive value of baselineOncology letters · 2021
    Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prioty Islama Winship Cancer Institute , Emory University , Atlanta , GA , USA.
Jordan Goldsteina Winship Cancer Institute , Emory University , Atlanta , GA , USA.
Christopher R Flowersa Winship Cancer Institute , Emory University , Atlanta , GA , USA.
Emory University · US

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
Mentored Patient Oriented Research in LymphomaK24CA208132 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FLOWERS, CHRISTOPHER R · 2016 to 2020
$822k
NCI NIH HHS K24 CA208132NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

[18F] fluorodeoxyglucose (FDG) - positron emission tomography (PET)/computed tomography (CT) is used to stage and assess response in diffuse large B-cell lymphoma (DLBCL), though the prognostic value of tumor metrics calculated from interim scans remains unsolved. We investigated the predictive value of interim and end-of-treatment (EOT) metabolic tumor volume (MTV), and total lesion glycolysis (TLG) on progression-free survival (PFS) at 24 months in patients with DLBCL treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). Controlling for pretreatment MTV, a positive interim MTV was highly correlated with (0.86) and a significant predictor of a positive EOT MTV (

Indexed as

Positron-Emission TomographyPositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBiomarkersCyclophosphamideDoxorubicinFemaleFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedLymphoma, Large B-Cell, DiffuseMaleMiddle AgedBiomarkersCyclophosphamideDoxorubicinFluorodeoxyglucose F18PrednisoneR-CHOP protocolRituximabVincristinediffuse large B cell lymphomametabolic tumor volumePrognostication

Identifiers

PMID30714446
PMCPMC6635064
OpenAlexW2912329422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.