Evidence map›Paper›PMID 30714386›Full record

ArticleAIDS care2019

Depression, social support, and stigma as predictors of quality of life over time: results from an Asha-based HIV/AIDS intervention in India.

Dana Rose Garfin, Sanghyuk S Shin, Maria L Ekstrand, Kartik Yadav, Catherine L Carpenter, Sanjeev Sinha, Adeline M Nyamathi

Registry-linked trialAbstract read
In one paragraph

Article in AIDS care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07209917 (Secondary Cervical Cancer Prevention of Vulnerable Women With Human Papillomavirus), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07209917 narecruitingnot on this mapstarted 2026, after this paper: background citation

Secondary Cervical Cancer Prevention of Vulnerable Women With Human Papillomavirus (HPV) and Human Immunodeficiency Virus (HIV) Co-infection in India

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2029Enrolled348ConditionsCervical Cancer, Human Papillomavirus (HPV) Infection, Human Immunodeficiency Virus (HIV) InfectionArmsSAKHI HPV Intervention, Enhanced Standard of Care (SOC+)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dana Rose Garfina Sue & Bill Gross School of Nursing , University of California , Irvine , CA , USA.
Sanghyuk S Shina Sue & Bill Gross School of Nursing , University of California , Irvine , CA , USA.
Maria L Ekstrandb UCSF School of Medicine , San Francisco , CA , USA.
Kartik Yadava Sue & Bill Gross School of Nursing , University of California , Irvine , CA , USA.
Catherine L Carpenterc UCLA Center for Human Nutrition , David Geffen School of Medicine at UCLA , Los Angeles , CA , USA.
Sanjeev Sinhad Department of Medicine , All India Institute of Medical Sciences , New Delhi , India.
Adeline M Nyamathia Sue & Bill Gross School of Nursing , University of California , Irvine , CA , USA.

Funding

Asha Improving Health and Nutrition of Indian Women with AIDS and Their ChildrenR01MH098728 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EKSTRAND, MARIA L., NYAMATHI, ADELINE M · 2013 to 2017
$2.9M
The Effect of Mixed-strain Mycobacterium tuberculosis Infections on TB Treatment Outcomes in Botswana: A Retrospective Cohort Study.K01AI118559 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIN, SANGHYUK SAM · 2015 to 2019
$670k
NIAID NIH HHS K01 AI118559NIMH NIH HHS R01 MH098728
6 · The paper itself

Abstract

Quality of life (QOL) is associated with better outcomes in HIV/AIDS populations. We explored predictors of improved QOL over time in 600 Women Living with HIV/AIDS (WLH/A) in India [mean age = 34.31, SD = 6.97], enrolled in a nurse-led-Asha (Accredited Social Health Activist) intervention. Trained local interviewers ascertained self-report data at baseline and six-month follow-up (post-intervention). Latent Class Analysis (LCA) identified constellations of responses on psychosocial indicators (depression, social support, internalized stigma and stigma fears); their relationship with QOL over time was examined. We identified three classes: Class 1) Highest Social Resources/Lowest Depression; Class 2) Some Social Resources/Highest Depression; and Class 3) Lowest Social Resources/Higher Depression. At baseline, Class 3 reported the lowest QOL (M = 0.25, SD = 0.26); Class 1 reported the highest (M = 0.37, SD = 0.33). Class 2's QOL did not differ from Class 3's QOL, likely due to the potent effects of high depression. At six-month follow-up, all groups reported improved QOL; class membership no longer predicted variability (contrast between Class 2 and 1 = -0.05, 95% CI = -0.14, 0.04; contrast between Class 3 and 1 = 0.01, 95% CI = -0.03, 0.05; contrast between Class 3 and 2 = 0.07, 95% CI = -0.02, 0.16). Psychosocial indicators are important predictors of QOL; an Asha-supported approach may have broad applicability to improve QOL in WLH/A in India.

Indexed as

Social StigmaSocial SupportAdultAntiretroviral Therapy, Highly ActiveDepressionFemaleHIV InfectionsHumansIndiaMaleMiddle AgedQuality of LifeSelf ReportAIDSdepressionHIVLatent Class Analysisquality of lifesocial supportstigma

Identifiers

PMID30714386
PMCPMC6995752

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.