Evidence map›Paper›PMID 30714353›Full record

Observational studyActa ophthalmologica2019

Retinal oxygen saturation in 1461 healthy children aged 7-19 and its associated factors.

Xiaoxiao Liu, Xiangui He, Yao Yin, Bo Zhang, Sifei Sun, Jianfeng Zhu, Haidong Zou, Ling Wang, Xun Xu

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Acta ophthalmologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Observational
  2. Observational
  3. Article
  4. Retinal oximetry: new insights into ocular and systemic diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults.Investigative ophthalmology & visual science · 2023
    Observational
  10. Article
  11. Retinal Vascular Oxygen Saturation in Adults With Anisometropia.Translational vision science & technology · 2023
    Observational
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoxiao LiuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.ORCID http://orcid.org/0000-0001-7193-8264
Xiangui HeDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.ORCID http://orcid.org/0000-0002-8938-1879
Yao YinDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
Bo ZhangDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
Sifei SunJiading Center for Disease Prevention and Control, Shanghai, China.
Jianfeng ZhuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
Haidong ZouDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.ORCID http://orcid.org/0000-0002-6831-7560
Ling WangDepartment of Maternal and Child Health, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.
Xun XuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.ORCID http://orcid.org/0000-0002-4246-4343

Funding

Excellent Young Talent Training Project of Shanghai Health and Family Planning Commission 2017YQ019Key Discipline of Public Health-Eye Health in Shanghai 15GWZK060115GWZK0601National Natural Science Foundation of China 81570851National Natural Science Foundation of China for Young Staff 81402695Overseas High-end Research Team-Eye Health in Shanghai GWTD2015S08Three-year Action Program of Shanghai Municipality for Strengthening the Construction of the Public Health System (2015-2017) 2015-2017Three-year Action Program of Shanghai Municipality for Strengthening the Construction of the Public Health System (2015-2017) GWIV-13.2
6 · The paper itself

Abstract

purposeThe aim of the present study was to investigate age-specific normative retinal oxygen saturation values and explore the associated factors in healthy Chinese school-aged children with different refractive statuses.

designPopulation-based observational cross-sectional study.

methodsChildren aged 7-19 years were enrolled. Each participant underwent a series of comprehensive ocular examinations, including axial length (AL), cycloplegic refraction and Oxymap T1 imagery following cycloplegia. The acquired oximetry images were measured, and the values of the retinal oxygen saturation parameters were calculated. The independent factors of the retinal oxygen saturation were analysed using multiple linear regression. The oxygen saturation of retinal arteries (SaO

resultsIn total, 1461 participants were included in the study. The mean age of the participants was 12.1 ± 3.2 years, and 53.0% were boys. The mean SaO

conclusionsOur population-based study provides age-specific profiles of retinal oxygen saturation in Chinese children and adolescents. Older age and longer AL were important independent factors of increased retinal oxygen saturation.

Indexed as

AdolescentChildCross-Sectional StudiesFemaleHumansMaleOximetryOxygenOxygen ConsumptionReference ValuesRefraction, OcularRegional Blood FlowRetinaRetinal VesselsYoung AdultOxygenchildrenmyopiaoxygen saturationretinal vessel

Identifiers

PMID30714353
PMCPMC6590240

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.