Evidence map›Paper›PMID 30714001›Full record

ArticleJournal of spine surgery (Hong Kong)2018

Cost-utility of revisions for cervical deformity correction warrants minimization of reoperations.

Samantha R Horn, Peter G Passias, Aaron Hockley, Renaud Lafage, Virginie Lafage, Hamid Hassanzadeh, Jason A Horowitz, Cole A Bortz, Frank A Segreto, Avery E Brown and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 1 country.

Samantha R HornDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Peter G PassiasDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Aaron HockleyDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Renaud LafageDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York City, NY, USA.
Virginie LafageDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York City, NY, USA.
Hamid HassanzadehDepartment of Orthopedic Surgery, University of Virginia Medical Center, Charlottesville, VA, USA.
Jason A HorowitzDepartment of Orthopedic Surgery, University of Virginia Medical Center, Charlottesville, VA, USA.
Cole A BortzDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Frank A SegretoDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Avery E BrownDepartment of Orthopaedics, NYU Langone Medical Center-Orthopaedic Hospital, New York, NY, USA.
Justin S SmithDepartment of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, USA.
Daniel M SciubbaDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Gregory M MundisDepartment of Orthopaedic Surgery, Scripps Spine Center, La Jolla, California, USA.
Michael P KelleyDepartment of Orthopaedic Surgery, Washington University Orthopedics, Chesterfield, MO, USA.
Alan H DanielsDepartment of Orthopaedic Surgery, Brown University Medical Center, Providence, Rhode Island, USA.
Douglas C BurtonDepartment of Orthopaedic Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
Robert A HartDepartment of Orthopaedic Surgery, Swedish Neuroscience Institute, Seattle, WA, USA.
Frank J SchwabDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York City, NY, USA.
Shay BessDepartment of Orthopaedic Surgery, Presbyterian/St. Luke's Medical Center, Rocky Mountain Hospital for Children, Denver, CO, USA.
Christopher I ShaffreyDepartment of Orthopedic Surgery, University of Virginia Medical Center, Charlottesville, VA, USA.
Richard A HostinDepartment of Orthopaedic Surgery, Baylor Scoliosis Center, Dallas, Texas, USA.
Christopher P AmesDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
International Spine Study Group
NYU Langone Health · USHospital for Special Surgery · USBrown University · USScripps Institution of Oceanography · USUniversity of Virginia Medical Center · USRocky Mountain Hospital for Children · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical deformity (CD) surgery has become increasingly more common and complex, which has also led to reoperations for complications such as distal junctional kyphosis (DJK). Cost-utility analysis has yet to be used to analyze CD revision surgery in relation to the cost-utility of primary CD surgeries. The aim of this study was to determine the cost-utility of revision surgery for CD correction.

methodsRetrospective review of a multicenter prospective CD database. CD was defined as at least one of the following: C2-C7 Cobb >10°, cervical lordosis (CL) >10°, cervical sagittal vertical axis (cSVA) >4 cm, chin-brow vertical angle (CBVA) >25°. Quality-adjusted life year (QALY) were calculated by EuroQol Five-Dimensions questionnaire (EQ-5D) and Neck Disability Index (NDI) mapped to SF-6D index and utilized a 3% discount rate to account for residual decline to life expectancy (men: 76.9 years, women: 81.6 years). Medicare reimbursement at 30 days assigned costs for index procedures (9+ level posterior fusion, 4-8 level posterior fusion with anterior fusion, 2-3 level posterior fusion with anterior fusion, 4-8 level anterior fusion) and revision fusions (2-3 level, 4-8 level, or 9+ level posterior refusion). Cost per QALY gained was calculated.

resultsEighty-nine CD patients were included (61.6 years, 65.2% female). CD correction for these patients involved a mean 7.7±3.7 levels fused, with 34% combined approach surgeries, 49% posterior-only and 17% anterior-only, 19.1% three-column osteotomy. Costs for index surgeries ranged from $20,001-55,205, with the average cost for this cohort of $44,318 and cost per QALY of $27,267. Eleven revision surgeries (mean levels fused 10.3) occurred up to 1-year, with an average cost of $41,510. Indications for revisions were DJK (5/11), neurologic impairment [4], infection [1], prominent/painful instrumentation [1]. Average QALYs gained was 1.62 per revision patient. Cost was $28,138 per QALY for reoperations.

conclusionsCD revisions had a cost of $28,138 per QALY, in addition to the $27,267 per QALY for primary CD surgeries. For primary CD patients, CD surgery has the potential to be cost effective, with the caveats that a patient livelihood extends long enough to have the benefits and durability of the surgery is maintained. Efforts in research and surgical technique development should emphasize minimization of reoperation causes just as DJK that significantly affect cost utility of these surgeries to bring cost-utility to an acceptable range.

Indexed as

Cervical deformity (CD)costcost-utilityeconomic burdenreoperation cost

Identifiers

PMID30714001
PMCPMC6330577
OpenAlexW2898654188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.