Evidence map›Paper›PMID 30713633›Full record

ArticleChemical science2019

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K

Changdong Liu, Bo Zhou, Yanyan Geng, Dick Yan Tam, Rui Feng, Haitao Miao, Naining Xu, Xiao Shi, Yingying You, Yuning Hong and 4 more

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. G-Quadruplex Structures Formed by Human Telomere andInternational journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. SelectiveJournal of medicinal chemistry · 2022
    Article
  12. Phen-DCAngewandte Chemie (International ed. in English) · 2022
    Article
  13. Article
  14. Thermodynamic Stability of G-Quadruplexes: Impact of Sequence and Environment.Chembiochem : a European journal of chemical biology · 2021
    Review
  15. Article
  16. DNA G-Quadruplexes Contribute to CTCF Recruitment.International journal of molecular sciences · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Changdong LiuDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Bo ZhouDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Yanyan GengDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Dick Yan TamDepartment of Biology and Chemistry , City University of Hong Kong , 83 Tat Chee Avenue , Kowloon Tong , Hong Kong SAR , China.
Rui FengDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Haitao MiaoDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Naining XuDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Xiao ShiDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Yingying YouDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.
Yuning HongDepartment of Chemistry , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China.ORCID 0000-0002-8085-1651
Ben Zhong TangDepartment of Chemistry , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China.
Pik Kwan LoDepartment of Biology and Chemistry , City University of Hong Kong , 83 Tat Chee Avenue , Kowloon Tong , Hong Kong SAR , China.ORCID 0000-0001-5255-1718
Vitaly KuryavyiStructural Biology Program , Memorial Sloan-Kettering Cancer Center , New York , NY , USA . Email: v.kuryavyi@gmail.com.
Guang ZhuDivision of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: gzhu@ust.hk.ORCID 0000-0003-3802-3446

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Guanine tracts of human telomeric DNA sequences are known to fold into eight different four-stranded structures that vary by the conformation of guanine nucleotides arranged in the stack of G-tetrads in their core and by different kinds and orders of connecting loops, called G-quadruplexes. Here, we present a novel G-quadruplex structure formed in K

Identifiers

PMID30713633
PMCPMC6330691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.