Evidence map›Paper›PMID 30713606›Full record

ArticleVeterinary research forum : an international quarterly journal2018

DNA damage in dental pulp mesenchymal stem cells: An

Jaime Sardá Aramburú Junior, Tiago Luis Eilers Treichel, Saulo Tadeu Lemos Pinto Filho, Sergio Alexandre Gehrke, Alencar Kolinski Machado, Francine Carla Cadoná, Ivana Beatrice Mânica da Cruz, Ney Luis Pippi

Open access · greenAbstract read
In one paragraph

Article in Veterinary research forum : an international quarterly journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jaime Sardá Aramburú JuniorGraduate Program in Veterinary Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
Tiago Luis Eilers TreichelGraduate Program in Veterinary Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
Saulo Tadeu Lemos Pinto FilhoGraduate Program in Veterinary Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
Sergio Alexandre GehrkeBiotecnos Research Center, Santa Maria, Rio Grande do Sul, Brazil; Catholic University of Uruguay, Montevideo, Uruguay.
Alencar Kolinski MachadoMorphology Department, Federal University of Santa Maria, Santa Maria, Brazil.
Francine Carla CadonáMorphology Department, Federal University of Santa Maria, Santa Maria, Brazil.
Ivana Beatrice Mânica da CruzMorphology Department, Federal University of Santa Maria, Santa Maria, Brazil.
Ney Luis PippiGraduate Program in Veterinary Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
Universidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the potential use of a DNA comet assay, DNA fragmentation fluorimetric assay and reactive oxygen species levels as potential biomarkers of genome conditions of dental pulp stem cells (DPSCs) isolated from dog canine teeth. Mesenchymal stem cells were isolated from the dental pulp collected from dog teeth. The results obtained suggest the ideal moment for clinical application of cellular therapy for this type of cell. The cell culture was maintained with Dulbecco's modified Eagle's medium supplemented with 10.00% fetal bovine serum for eight passages. During each passage, cell proliferation, oxidative stress and level of DNA fragmentation were assessed by3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium (MTT) assay, testing 2,7 dichlorodihydro-fluorescein-diacetate and PicoGreen

Indexed as

Dental pulpDNA damageGenotoxicityMesenchymal stem cellOxidative stress

Identifiers

PMID30713606
PMCPMC6346493
OpenAlexW2912568767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.