Evidence map›Paper›PMID 30713581›Full record

ArticleNature photonics2018

Nano-optic endoscope for high-resolution optical coherence tomography

Hamid Pahlevaninezhad, Mohammadreza Khorasaninejad, Yao-Wei Huang, Zhujun Shi, Lida P Hariri, David C Adams, Vivien Ding, Alexander Zhu, Cheng-Wei Qiu, Federico Capasso and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nature photonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 400 citations in OpenAlex.

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  10. Water-Immersed GaP Huygens' Meta-Optics for Visible Structured Light Generation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Hamid PahlevaninezhadHarvard Medical School and Massachusetts General Hospital, Boston MA 02114, United States.
Mohammadreza KhorasaninejadJohn A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge MA 02138, United States.
Yao-Wei HuangJohn A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge MA 02138, United States.
Zhujun ShiDepartment of Physics, Harvard University, Cambridge, MA 02138, United States.
Lida P HaririHarvard Medical School and Massachusetts General Hospital, Boston MA 02114, United States.
David C AdamsHarvard Medical School and Massachusetts General Hospital, Boston MA 02114, United States.
Vivien DingJohn A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge MA 02138, United States.
Alexander ZhuJohn A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge MA 02138, United States.
Cheng-Wei QiuDepartment of Electrical and Computer Engineering, National University of Singapore, 117583 Singapore, Singapore.
Federico CapassoJohn A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge MA 02138, United States.
Melissa J SuterHarvard Medical School and Massachusetts General Hospital, Boston MA 02114, United States.
Harvard University · USNational University of Singapore · SG

Funding

Phenotyping Asthma for Bronchial Thermoplasty: Airway Smooth Muscle Structure and FunctionR01HL133664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SUTER, MELISSA J · 2017 to 2021
$3.7M
Increasing the diagnostic yield of low-risk bronchial biopsy in the evaluation ofR01CA167827 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BOUMA, BRETT E, SUTER, MELISSA J · 2013 to 2017
$2.7M
NCI NIH HHS R01 CA167827NHLBI NIH HHS R01 HL133664
6 · The paper itself

Abstract

Acquisition of high-resolution images from within internal organs using endoscopic optical imaging has numerous clinical applications. However, difficulties associated with optical aberrations and the trade-off between transverse resolution and depth-of-focus significantly limit the scope of applications. Here, we integrate a metalens, with the ability to modify the phase of incident light at sub-wavelength level, into the design of an endoscopic optical coherence tomography catheter (termed nano-optic endoscope) to achieve near diffraction-limited imaging through negating non-chromatic aberrations. Remarkably, the tailored chromatic dispersion of the metalens in the context of spectral interferometry is utilized to maintain high-resolution imaging beyond the input field Rayleigh range, easing the trade-off between transverse resolution and depth-of-focus. We demonstrate endoscopic imaging both in resected human lung specimens and in sheep airways

Identifiers

PMID30713581
PMCPMC6350822
OpenAlexW2883697371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.