ArticleFrontiers in plant science2019
The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
Article in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 189 citations in OpenAlex.
- A bHLH121/URI-ANAC017-MAT1/SAM1 regulatory cascade controls iron homeostasis in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Cross-Species Plasticity and Divergence Under Alkaline Soil Signature Conditions Differentiating PYE From FIT Target Transcripts in the Arabidopsis thaliana Ferrome.Plant, cell & environment · 2026Article
- OsbHLH064, an IVb bHLH Transcription Factor, Regulates Iron Homeostasis and Enhances Grain Fe Accumulation in Rice.Plant biotechnology journal · 2026Article
- Article
- Iron status modulates cadmium tolerance: mechanistic insights fromFrontiers in plant science · 2026Article
- Competition Binding of CmbHLH1L and CmNLP6/7L to CmbHLH63 Modulates Leaf Senescence in Chrysanthemum.Plant biotechnology journal · 2025Article
- Abscisic acid regulates iron accumulation in plant seeds via the PYLs-bHLH IVc-YSLs module.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Physiological, Biochemical, and Transcriptomic Responses to Iron Deficiency in Two Potato Varieties.Plants (Basel, Switzerland) · 2025Article
- Calmodulin-like protein MdCML15 interacts with MdBT2 to modulate iron homeostasis in apple.Horticulture research · 2024Article
- The activation of iron deficiency responses of grapevine rootstocks is dependent to the availability of the nitrogen forms.BMC plant biology · 2024Article
- Transcription factors involved in plant responses to cadmium-induced oxidative stress.Frontiers in plant science · 2024Review
- HapX-mediated H2B deub1 and SreA-mediated H2A.Z deposition coordinate in fungal iron resistance.Nucleic acids research · 2023Article
- BRUTUS-LIKE (BTSL) E3 ligase-mediated fine-tuning of Fe regulation negatively affects Zn tolerance of Arabidopsis.Journal of experimental botany · 2023Article
- Beyond NPK: Mineral Nutrient-Mediated Modulation in Orchestrating Flowering Time.Plants (Basel, Switzerland) · 2023Review
- The Role of Iron in Phytopathogenic Microbe-Plant Interactions: Insights into Virulence and Host Immune Response.Plants (Basel, Switzerland) · 2023Review
- Supramolecular Arrangement of Lignosulfonate-Based Iron Heteromolecular Complexes and Consequences of Their Interaction with CaJournal of agricultural and food chemistry · 2023Article
- Article
- Evidence ThatPlants (Basel, Switzerland) · 2023Article
- The Molecular Mechanism ofPlants (Basel, Switzerland) · 2023Article
- Entomopathogenic Fungi-Mediated Solubilization and Induction of Fe Related Genes in Melon and Cucumber Plants.Journal of fungi (Basel, Switzerland) · 2023Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is one of the most important micronutrients in plants as it is involved in many cellular functions (e.g., photosynthesis and respiration). Any defect in iron availability will affect plant growth and development as well as crop yield and plant product quality. Thus, iron homeostasis must be tightly controlled in order to ensure optimal absorption of this mineral element. Understanding mechanisms governing iron homeostasis in plants has been the focus of several studies during the past 10 years. These studies have greatly improved our understanding of the mechanisms involved, revealing a sophisticated iron-dependent transcriptional regulatory network. Strikingly, these studies have also highlighted that this regulatory web relies on the activity of numerous transcriptional regulators that belong to the same group of transcription factors (TF), the bHLH (basic helix-loop-helix) family. This is best exemplified in Arabidopsis where, to date, 16 bHLH TF have been characterized as involved in this process and acting in a complex regulatory cascade. Interestingly, among these bHLH TF some form specific clades, indicating that peculiar function dedicated to the maintenance of iron homeostasis, have emerged during the course of the evolution of the green lineage. Within this mini review, we present new insights on the control of iron homeostasis and the involvement of bHLH TF in this metabolic process.
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