Evidence map›Paper›PMID 30713538›Full record

Trial reportFrontiers in immunology2018

A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection.

Felicity Hartnell, Anthony Brown, Stefania Capone, Jakub Kopycinski, Carly Bliss, Shokouh Makvandi-Nejad, Leo Swadling, Emma Ghaffari, Paola Cicconi, Mariarosaria Del Sorbo and 14 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
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  17. Review
  18. Characterizing Hepatitis C Virus-Specific CD4Hepatology (Baltimore, Md.) · 2020
    Observational
  19. Article
  20. Innovations in HIV-1 Vaccine Design.Clinical therapeutics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 8 institutions in 6 countries.

Felicity HartnellNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Anthony BrownNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Stefania CaponeReiThera s.r.l., Rome, Italy.
Jakub KopycinskiNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Carly BlissNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Shokouh Makvandi-NejadNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Leo SwadlingNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Emma GhaffariNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Paola CicconiNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Mariarosaria Del SorboReiThera s.r.l., Rome, Italy.
Roberta SbrocchiReiThera s.r.l., Rome, Italy.
Ilaria EspositoNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Ventzislav VassilevGlaxoSmithKline Vaccines, Brussels, Belgium.
Paula MarriottCentre for Clinical Vaccinology and Tropical Medicine, Jenner Institute, University of Oxford, Oxford, United Kingdom.
Clair M GardinerSchool of Biochemistry and Immunology, Trinity College, Dublin, Ireland.
Ciaran BannanSt James' Hospital, Dublin, Ireland.
Colm BerginSt James' Hospital, Dublin, Ireland.
Matthias HoffmannDivision of Infectious Diseases and Hospital Epidemiology, Kantonsspital St Gallen, St Gallen, Switzerland.
Bethany TurnerNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Alfredo NicosiaKeires AG, Basel, Switzerland.
Antonella FolgoriReiThera s.r.l., Rome, Italy.
Tomáš HankeJenner Institute Laboratories, University of Oxford, Oxford, United Kingdom.
Eleanor BarnesNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Lucy DorrellNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
University of Oxford · GBOxford BioMedica (United Kingdom) · GBSt. James's Hospital · IECeinge Biotecnologie Avanzate (Italy) · ITGlaxoSmithKline (Belgium) · BEJenner Institute · GBKantonsspital St. Gallen · CHTrinity College Dublin · IE

Funding

Medical Research Council G0701669Medical Research Council G0701694Medical Research Council G1001757Medical Research Council MR/K010239/1Medical Research Council MR/N023668/1MRF_ MRF-044-0001-RG-SWADL
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenoviruses, SimianGenetic VectorsAdolescentAdultAnimalsAntibodies, NeutralizingAntibodies, ViralCoinfectionCytokinesEnzyme-Linked Immunosorbent AssayFemaleHepatitis CHIV InfectionsHumansMaleMiddle AgedAntibodies, NeutralizingAntibodies, ViralCytokinesViral Vaccinesclinical trialcoadministrationconserved regionHCV (hepatitis C virus)HIV-1non-structural protein (NS)transcriptomics analysisvaccine

Identifiers

PMID30713538
PMCPMC6346592
OpenAlexW2908865719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.