Evidence map›Paper›PMID 30713531›Full record

ArticleFrontiers in microbiology2018

Microbial-Driven Butyrate Regulates Jejunal Homeostasis in Piglets During the Weaning Stage.

Xi Zhong, Zhongwei Zhang, Shujin Wang, Lili Cao, Lin Zhou, Aomin Sun, Zhendong Zhong, Miranda Nabben

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Xi ZhongIntensive Care Unit, West China Hospital, Sichuan University, Chengdu, China.
Zhongwei ZhangIntensive Care Unit, West China Hospital, Sichuan University, Chengdu, China.
Shujin WangDepartment of Genetics and Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Lili CaoMedical School, Chengdu University, Chengdu, China.
Lin ZhouShenzhen Premix Inve Nutrition, Co., Ltd., Shenzhen, China.
Aomin SunDepartment of Genetics and Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Zhendong ZhongChengdu LiLai Biotechnology, Co. Ltd., Chengdu, China.
Miranda NabbenDepartment of Genetics and Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Maastricht University · NLChengdu Medical College · CNChengdu Organic Chemicals (China) · CNSichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbe-derived butyrate plays an important role in the gut health of young mammals during the weaning stage. A greater understanding of how butyrate regulates intestinal development is necessary for overcoming post-weaning diarrheal diseases. We aimed to investigate whether jejunal microbial metabolite butyrate modulates the apoptosis/proliferation balance and immune response in piglets during the post-weaning period of the first 3 weeks of life. On the one hand, during the first week post-weaning, the relative abundances of the dominant bacterial families

Indexed as

apoptosisbutyrateinflammatory responsejejunummicrobiotaproliferationSus scrofaweaned

Identifiers

PMID30713531
PMCPMC6345722
OpenAlexW2910906439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.