Evidence map›Paper›PMID 30713422›Full record

ArticleMolecular vision2018

Rescue of cone function in cone-only

Christin Hanke-Gogokhia, Vince A Chiodo, William W Hauswirth, Jeanne M Frederick, Wolfgang Baehr

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Gene therapy rescues cone function inMolecular therapy. Advances · 2026
    Article
  2. Article
  3. Review
  4. Nephronophthisis: a pathological and genetic perspective.Pediatric nephrology (Berlin, Germany) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Gene therapy reforms photoreceptor structure and restores vision in NPHP5-associated Leber congenital amaurosis.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  9. Bardet-Biedl syndrome-7 (Ophthalmic genetics · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christin Hanke-GogokhiaDepartment of Ophthalmology, John A. Moran Eye Center, University of Utah Health Science Center, Salt Lake City, UT.
Vince A ChiodoDepartment of Ophthalmology, University of Florida, Gainesville, FL.
William W HauswirthDepartment of Ophthalmology, University of Florida, Gainesville, FL.
Jeanne M FrederickDepartment of Ophthalmology, John A. Moran Eye Center, University of Utah Health Science Center, Salt Lake City, UT.
Wolfgang BaehrDepartment of Ophthalmology, John A. Moran Eye Center, University of Utah Health Science Center, Salt Lake City, UT.
University of Florida · USUniversity of Utah · US

Funding

University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI PAUL STEVEN BERNSTEIN · 2005 to 2026
$14.6M
Translational Research for Retinal Degeneration TherapiesR01EY017549 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BELTRAN, WILLIAM A. · 2007 to 2024
$14.1M
RETINAL PHOTORECEPTOR CYCLIC GMP PHOSPHODIESTERASER01EY008123 · NEI · UNIVERSITY OF UTAH · PI BAEHR, WOLFGANG · 1990 to 2019
$7.8M
Membrane Protein Transport in PhotoreceptorsR01EY019298 · NEI · UNIVERSITY OF UTAH · PI BAEHR, WOLFGANG · 2009 to 2018
$3.7M
NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY008123NEI NIH HHS R01 EY017549NEI NIH HHS R01 EY019298
6 · The paper itself

Abstract

Purpose: Recessive mutations in the human Methods: Results: In the Conclusions:

Indexed as

AdenoviridaeAmino Acid SequenceAnimalsAxonemeBasic-Leucine Zipper Transcription FactorsCalmodulin-Binding ProteinsCiliaCrosses, GeneticCyclic Nucleotide Phosphodiesterases, Type 6Disease Models, AnimalEye ProteinsFemaleGene Expression RegulationGenetic TherapyGenetic VectorsG-Protein-Coupled Receptor Kinase 1Basic-Leucine Zipper Transcription FactorsCalmodulin-Binding ProteinsCyclic Nucleotide Phosphodiesterases, Type 6Eye ProteinsGnat1 protein, mouseG-Protein-Coupled Receptor Kinase 1Grk1 protein, mouseGTP-Binding Protein alpha SubunitsIQCB1 protein, mouseMicrotubule-Associated ProteinsNrl protein, mousePde6a protein, mouseRP1 protein, mouseTransducin

Identifiers

PMID30713422
PMCPMC6334983
OpenAlexW2906998328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.