Evidence map›Paper›PMID 30713332›Full record

ArticleInternal medicine (Tokyo, Japan)2019

A Catastrophic Case of Idiopathic Cholesterol Crystal Embolism with Multiple Lethal Complications: A Labyrinth Underneath the Diagnosis of Skin Ulcers in Chronic Kidney Disease Patients.

Satoshi Kumakura, Takashi Nakamichi, Nonoka Suzuki, Shu Yamakage, Ayako Ishikawa, Emi Fujikura, Satoko Sato, Takeshi Aoki, Hiroaki Musha, Katsuko Kikuchi and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Satoshi KumakuraDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Takashi NakamichiDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Nonoka SuzukiDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Shu YamakageDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Ayako IshikawaDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Emi FujikuraDivision of Blood Purification, Tohoku University Hospital, Japan.
Satoko SatoDepartment of Pathology, Tohoku University Hospital, Japan.
Takeshi AokiDepartment of Surgery, Tohoku University Graduate School of Medicine, Japan.
Hiroaki MushaDepartment of Surgery, Tohoku University Graduate School of Medicine, Japan.
Katsuko KikuchiDepartment of Dermatology, Tohoku University Graduate School of Medicine, Japan.
Tasuku NagasawaDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Hiroshi SatoDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Sadayoshi ItoDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Mariko MiyazakiDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Tohoku University · JPTohoku University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old man was admitted to our hospital because of multiple refractory skin ulcers. Based on his severe systemic arterial calcification and severe calcium-phosphate imbalance due to severe kidney dysfunction, we initially considered calciphylaxis. However, a skin biopsy provided a diagnosis of cholesterol crystal embolization. Although we initiated hemodialysis, steroid treatment, and low-density lipoprotein-cholesterol apheresis, he died of multiple intestinal perforation. An autopsy showed cholesterol crystals occluding multiple organ arterioles. This case suggests that skin ulcers in patients with chronic kidney disease may be an important diagnostic hallmark and may be associated with several serious diseases.

Indexed as

Adrenal Cortex HormonesAgedBlood Component RemovalEmbolism, CholesterolHumansKidney Failure, ChronicMaleRenal DialysisSkin UlcerAdrenal Cortex Hormonesarteriolosclerosiscalciphylaxischolesterol crystal embolismchronic kidney diseasemultiple intestinal perforationskin ulcer

Identifiers

PMID30713332
PMCPMC6630139
OpenAlexW2911393178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.