Evidence map›Paper›PMID 30713294›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Methotrexate-associated Lymphoproliferative Disorder: A Rare Differential Diagnosis of Wheezes.

Mariko Ujino, Shoki Miyoshi, Naoya Sugimoto, Hidenori Arai, Yasunori Ota, Yuko Sasajima, Masafumi Kawamura, Hiroyuki Nagase, Masao Yamaguchi, Ken Ohta

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mariko UjinoDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Shoki MiyoshiDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Naoya SugimotoDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Hidenori AraiDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Yasunori OtaDepartment of Pathology, Teikyo University School of Medicine, Japan.
Yuko SasajimaDepartment of Pathology, Teikyo University School of Medicine, Japan.
Masafumi KawamuraDepartment of Surgery, Teikyo University School of Medicine, Japan.
Hiroyuki NagaseDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Masao YamaguchiDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Ken OhtaDivision of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Japan.
Fukujuji Hospital · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old woman was admitted for the evaluation of wheezes and a nodular lesion in the left lung field. She had been diagnosed with rheumatoid arthritis at 45 years of age and was continuously treated with methotrexate (MTX) at 8 mg/week. Bronchoscopic aspiration histology of a hilar lymph node suggested a lymphoproliferative disorder (LPD). After discontinuation of MTX, the lung nodule and wheezes disappeared. Although wheezes are not a usual manifestation of LPD, her clinical course clearly demonstrated an obvious relationship between LPD-induced airway narrowing and wheezes.

Indexed as

AgedAntirheumatic AgentsArthritis, RheumatoidDiagnosis, DifferentialFemaleHumansLymphoproliferative DisordersMethotrexateRespiratory SoundsAntirheumatic AgentsMethotrexateEpstein-Barr viruslymphoproliferative disordermethotrexaterheumatoid arthritiswheezes

Identifiers

PMID30713294
PMCPMC6630116
OpenAlexW2912216347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.