Evidence map›Paper›PMID 30713048›Full record

ReviewMayo Clinic proceedings2019

Androgens and Blood Pressure Control: Sex Differences and Mechanisms.

Jane F Reckelhoff

RetractedOpen access · bronzeAbstract readReview
In one paragraph

Review in Mayo Clinic proceedings, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Second to Fourth Digit Ratio (2D:4D) in Hypertension Disease.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Effect of Pituitary-Target Gland Axis on RAAS in the Context of COVID-19.International journal of medical sciences · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Sex-Specific Differences in Kidney Function and Blood Pressure Regulation.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

  • Reinstatement · 2019-02-01Date of Article and/or Notice Unknown · Notice - Limited or No Information · Retract and Replace · Temporary Removal · · date of retraction and reinstatement unknown, html page overwrite - no reasons given (1/22/22 AJA)
5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jane F ReckelhoffDepartment of Cell and Molecular Biology, Mississippi Center of Excellence in Perinatal Research and Women's Health Research Center, University of Mississippi Medical Center, Jackson. Electronic address: jreckelhoff@umc.edu.
University of Mississippi Medical Center · US

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI HALL, JOHN E · 1993 to 2018
$39.4M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
HUMORAL FACTORS IN GENDER DIFFERENCES IN BP CONTROLR01HL066072 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 2001 to 2015
$3.9M
Mechanisms of hypertension in women with polycystic ovary syndromeR01HL135089 · NHLBI · JOHN B. PIERCE LABORATORY, INC. · PI RECKELHOFF, JANE F, STACHENFELD, NINA · 2018 to 2021
$3.5M
Gender and susceptibility to kidney damage in high BP.R01HL069194 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 2001 to 2010
$2.5M
NHLBI NIH HHS P01 HL051971NHLBI NIH HHS R01 HL066072NHLBI NIH HHS R01 HL069194NHLBI NIH HHS R01 HL135089NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

The role that androgens play in mediating elevated blood pressure is unclear. Low levels of androgens in men and increased levels of androgens in women, as occurs with polycystic ovary syndrome (PCOS), are both associated with increased risk for cardiovascular disease and elevated blood pressure. We have used animal models to evaluate the potential mechanisms by which men and women have differential responses to androgens that affect regulation of blood pressure and the implications these may have for the health of men and women.

Indexed as

AndrogensAnimalsBlood PressureCardiovascular DiseasesFemaleHumansMaleModels, AnimalPolycystic Ovary SyndromeRenin-Angiotensin SystemSex DistributionSex FactorsTestosteroneAndrogensTestosterone

Identifiers

PMID30713048
PMCPMC6546172
OpenAlexW2914178393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.