Evidence map›Paper›PMID 30712520›Full record

ArticleEpidemiology and psychiatric sciences2019

Lifetime experience of multiple common mental disorders and 19-year mortality: results from a Canadian population-based cohort.

M Kingsbury, E Sucha, N J Horton, H Sampasa-Kanyinga, J M Murphy, S E Gilman, I Colman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and psychiatric sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mental disorders and total mortality after 20 years in an adult general population sample.European psychiatry : the journal of the Association of European Psychiatrists · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

M KingsburySchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
E SuchaSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
N J HortonDepartment of Mathematics and Statistics, Amherst College, Amherst, MA, USA.
H Sampasa-KanyingaSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
J M MurphyDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
S E GilmanSocial and Behavioral Sciences Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
I ColmanSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.ORCID https://orcid.org/0000-0001-5924-0277
University of Ottawa · CAAmherst College · USDalhousie University · CAJohns Hopkins University · US

Funding

Social determinants of child development and mental healthZIAHD008976 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GILMAN, STEPHEN · 2018 to 2025
$14.3M
LONGITUDINAL STUDY IN PSYCHIATRIC EPIDEMIOLOGYR01MH039576 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MURPHY, JANE M · 1985 to 2007
$2.1M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD008976-01NIMH NIH HHS R01 MH039576
6 · The paper itself

Abstract

aimsTo examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population.

methodsData came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcohol use disorders were assessed using the Diagnostic Interview Schedule (DIS). Vital status of participants through 2011 was determined using probabilistic linkages to the Canadian Mortality Database. Cox proportional hazard models with age at study entry as the time scale were used to investigate the relationship between DIS diagnoses and mortality, adjusted for participant education, smoking and obesity at baseline.

resultsResults suggested that mood and anxiety disorders rarely presented in isolation - the majority of participants experienced multiple psychiatric disorders over the lifetime. Elevated risk of death was found among men with both major depression and dysthymia (HR 2.56; 95% CI 1.12-5.89), depression and alcohol use disorders (HR 2.45; 95% CI 1.18-5.10) and among men and women who experienced both panic disorder and alcohol use disorders (HR 3.80; 95% CI 1.19-12.16).

conclusionThe experience of multiple mental disorders over the lifetime is extremely common, and associated with increased risk of mortality, most notably among men. Clinicians should be aware of the importance of considering contemporaneous symptoms of multiple psychiatric conditions.

Indexed as

AdultCanadaCohort StudiesFemaleHumansMaleMental DisordersAlcohol abusecommon mental disordersepidemiologyhealth outcomesmultimorbidity

Identifiers

PMID30712520
PMCPMC6679827
OpenAlexW2914837154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.