Evidence map›Paper›PMID 30712505›Full record

ArticleGut microbes2019

A murine model of diarrhea, growth impairment and metabolic disturbances with

Pedro Henrique Q S Medeiros, Solanka E Ledwaba, David T Bolick, Natasa Giallourou, Lauren K Yum, Deiziane V S Costa, Reinaldo B Oriá, Eileen M Barry, Jonathan R Swann, Aldo Ângelo M Lima and 2 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Development of a Novel mRNA Vaccine AgainstBioinformatics and biology insights · 2025
    Article
  5. International journal of molecular sciences · 2024
    Review
  6. Article
  7. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Functional assays to evaluate antibody-mediated responses againstFrontiers in cellular and infection microbiology · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Outer Membrane Vesicles Derived fromApplied and environmental microbiology · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Pedro Henrique Q S MedeirosCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.
Solanka E LedwabaCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.ORCID 0000-0002-9426-0131
David T BolickCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.
Natasa GiallourouDivision of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London , London , UK.ORCID 0000-0001-5081-7367
Lauren K YumDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia , Charlottesville , USA.
Deiziane V S CostaCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.
Reinaldo B OriáCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.
Eileen M BarryCenter for Vaccine Development, University of Maryland , Baltimore , USA.
Jonathan R SwannDivision of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London , London , UK.ORCID 0000-0002-6485-4529
Aldo Ângelo M LimaInstitute of Biomedicine, Federal University of Ceara , Fortaleza , Brazil.
Hervé AgaisseDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia , Charlottesville , USA.
Richard L GuerrantCenter for Global Health, Division of Infectious Diseases and International Health, University of Virginia , Charlottesville , USA.
Universidade Federal do Ceará · BRCenter for Global Health · USImperial College London · GBUniversity of Virginia · USUniversity of Maryland, Baltimore · US

Funding

Shigella Live Vector-Based Multivalent VaccineU19AI109776 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LEVINE, MYRON MAX · 2014 to 2018
$25.4M
Mechanisms of intracellular pathogen disseminationR01AI073904 · NIAID · YALE UNIVERSITY · PI AGAISSE, HERVE F · 2007 to 2022
$5.5M
Global Infectious Disease Research Training Program at UVAD43TW006578 · FIC · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUERRANT, RICHARD L · 2003 to 2018
$2.7M
FIC NIH HHS D43 TW006578NIAID NIH HHS R01 AI073904NIAID NIH HHS U19 AI109776
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsAnti-Bacterial AgentsBody WeightColonDiarrheaDysentery, BacillaryFecesIntestinal MucosaMetabolomeMice, Inbred C57BLMutationShigella flexneriType III Secretion SystemsZincAnti-Bacterial AgentsType III Secretion SystemsZincintestinal microbiotamouse modelShigellosisurine metabolomicszinc deficiency

Identifiers

PMID30712505
PMCPMC6748602
OpenAlexW2912968892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.