Evidence map›Paper›PMID 30712240›Full record

SynthesisCurrent atherosclerosis reports2019

High-Intensity Interval Training in Patients with Type 2 Diabetes Mellitus: a Systematic Review.

Djeniffer Elias da Silva, Antônio José Grande, Leonardo Roever, Gary Tse, Tong Liu, Giuseppe Biondi-Zoccai, Joni Márcio de Farias

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current atherosclerosis reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Effect of HIIT Training Modality in People with Pre-Diabetes.Journal of functional morphology and kinesiology · 2026
    Article
  3. Review
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  6. Review
  7. Article
  8. Review
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  11. Article
  12. Review
  13. Article
  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Djeniffer Elias da SilvaUniversity of the Far South Catarinense - UNESC, Criciúma, Santa Catarina, Brazil.
Antônio José GrandeState University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Leonardo RoeverDepartment of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil.
Gary TseDepartment of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hos-pital of Tianjin Medical University, Tianjin, China.
Giuseppe Biondi-ZoccaiDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Joni Márcio de FariasDepartment of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China. jmf@unesc.net.
Chinese University of Hong Kong · CNSapienza University of Rome · ITSecond Hospital of Tianjin Medical University · CNUniversidade do Extremo Sul Catarinense · BRUniversidade Estadual de Mato Grosso do Sul · BRUniversidade Federal de Uberlândia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHigh-intensity exercise may beneficially impact on insulin sensitivity. However, there is still uncertainty on the actual impact of high-intensity interval training (HIIT) on chronic physiologic adaptations among patients with type 2 diabetes mellitus (T2DM). We aimed to systematically search and appraise the evidence base on the effects of HIIT in comparison to mild- or moderate-intensity interval training (MMIIT) on glycemic control inT2DM. RECENT

findingsA total of 5 RCT met the inclusion criteria. Most studies presented significant differences for weight and BMI with HIIT, and with both interventions for total body fat. For the other health-related variables (systolic and diastolic BP, fasting cholesterol, LDL and HDL, triglycerides, fasting glucose, and HbAc1), only 1 study provided detailed results for HIIT, showing significant differences for systolic BP and HDL cholesterol in 2 studies, total cholesterol, LDL, and triglycerides, whereas for MIIT, only 1 study brought significant differences for LDL cholesterol. For glucose levels, significant differences were reported in 4 studies for both HIIT and MMIT, but only two studies used the percentage delta assessment tool, whereas 1 study only showed significant improvements for HIIT. The number of studies for the analysis is not precise as to the statements regarding the results of the intervention proposed for this public, since they do not allow identifying a consistency of the findings, not presenting diversity between the training methods and the different methods of volume control and intensity of training.

Indexed as

High-Intensity Interval TrainingAdultAgedAged, 80 and overBlood GlucoseBlood PressureCholesterol, HDLCholesterol, LDLDiabetes Mellitus, Type 2Exercise TherapyFemaleGlycated HemoglobinHumansInsulin ResistanceMaleMiddle AgedBlood GlucoseCholesterol, HDLCholesterol, LDLGlycated Hemoglobinhemoglobin A1c protein, humanTriglyceridesDiabetes mellitusExerciseHigh-intensity interval training

Identifiers

PMID30712240
OpenAlexW2914643187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.