Evidence map›Paper›PMID 30712164›Full record

ArticleLa Radiologia medica2019

Identification of residual-recurrent cholesteatoma in operated ears: diagnostic accuracy of dual-energy CT and MRI.

Giovanni Foti, Alberto Beltramello, Giorgio Minerva, Matteo Catania, Massimo Guerriero, Sergio Albanese, Giovanni Carbognin

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Article in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Key Techniques and Outcome Analysis of Endoscopic Mastoid Revision Surgery.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  3. Article
  4. MRI-DWI detection of residual cholesteatoma: moving toward an optimum follow-up scheme.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giovanni FotiDepartment of Radiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy. gfoti81@yahoo.it.ORCID http://orcid.org/0000-0002-1426-2402
Alberto BeltramelloDepartment of Radiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Giorgio MinervaDepartment of Otorhinolaryngology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Matteo CataniaDepartment of Radiology, University of Verona, Verona, Italy.
Massimo GuerrieroDepartment of Computer Science, University of Verona, Verona, Italy.
Sergio AlbaneseDepartment of Otorhinolaryngology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Giovanni CarbogninDepartment of Radiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Ospedale Sacro Cuore Don Calabria · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to compare the diagnostic accuracy of magnetic resonance imaging (MRI) and dual-energy computed tomography (DECT) to identify residual-recurrent cholesteatoma using the second-look surgery as the reference standard.

methodsThis prospective, institutional review board-approved study included 19 consecutive patients (11 males and 8 females; mean age of 62.2, range 34-80 years). Since five patients were studied bilaterally, a total of 24 ears were evaluated with DECT and MRI between February 2017 and June 2018. Any abnormal middle ear attenuation on high-resolution CT images (HRCT) or DECT color-coded maps, and any abnormal signal on MRI images was evaluated by four experienced radiologists. Diagnostic accuracy values of HRCT, DECT maps and CT numbers (by using receiver operator curves) and MRI were compared. Interobserver and intraobserver agreement were calculated.

resultsResidual-recurrent cholesteatoma was diagnosed at surgery in 16/24 ears (66.6%). MRI and DECT revealed a total of 15/16 and 14/16 cholesteatomas, respectively. The sensitivity, specificity, PPV and NPV and accuracy of MRI and DECT were 93.7, 87.5, 93.7, 87.5, and 91.6% and 87.5, 87.5, 93.3, 87.5 and 87.5%, respectively. CT numbers were significantly different between positive (mean 57.6 HU, range - 65, 112 HU) and negative cases (mean 5.4 HU, range - 100, 66 HU) with p < 0.001. The interobserver and intraobserver agreement were k = 0.87 and k = 0.83, respectively.

conclusionDECT may provide an accurate demonstration of residual-recurrent middle ear cholesteatoma.

Indexed as

AdultAgedAged, 80 and overCholesteatoma, Middle EarFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesRecurrenceSecond-Look SurgerySensitivity and SpecificityTomography, X-Ray ComputedCholesteatomaDiffusion-weighted imagesDual-energy CTMagnetic resonance imagingRecurrence

Identifiers

PMID30712164
OpenAlexW2913037647

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.