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ArticleClinical research in cardiology : official journal of the German Cardiac Society2019

Left atrial anterior line ablation using ablation index and inter-lesion distance measurement.

Francesco Santoro, Andreas Metzner, Natale Daniele Brunetti, Christian-H Heeger, Shibu Mathew, Bruno Reissmann, Christine Lemeš, Tilman Maurer, Thomas Fink, Laura Rottner and 4 more

Abstract read
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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Evaluation of ablation index-guided linear lesions formation for left atrial arrhythmia treatment.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  2. Article
  3. Characterizing lesion morphology of a novel diamond-tip temperature-controlled irrigated radiofrequency ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Voltage-guided ablation in persistent atrial fibrillation-favorable 1-year outcome and predictors.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  9. Article
  10. Atrial fibrillation ablation strategies and technologies: past, present, and future.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Review
  11. Article
  12. Article
  13. Pulmonary vein isolation treats symptomatic AF in a patient with Lamin A/C mutation: case report and review of the literature.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesco SantoroDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany. dr.francesco.santoro.it@gmail.com.ORCID http://orcid.org/0000-0001-9909-6513
Andreas MetznerDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Natale Daniele BrunettiDepartment of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Christian-H HeegerDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Shibu MathewDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Bruno ReissmannDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Christine LemešDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Tilman MaurerDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Thomas FinkDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Laura RottnerDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Osamu InabaDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Karl-Heinz KuckDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Feifan OuyangDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Andreas RilligDepartment of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAblation index (AI) is a novel ablation quality marker that incorporates contact force (CF), time and power in a weighted formula to provide accurate information about lesion formation during catheter ablation. This index has been evaluated for pulmonary vein isolation (PVI) but has not been systematically used for other left atrial (LA) procedures so far. The aim of this study is to evaluate the feasibility and efficacy of this index for LA anterior line (AL) ablation (LAALA).

methods30 consecutive patients with persistent atrial fibrillation or LA macro-reentrant tachycardia and large low-voltage area at the left atrial anterior wall were evaluated and divided into 2 groups: group 1 (15 pts) LAALA guided by CF; group 2 (15 pts) LAALA guided by AI target (500) and inter-lesion distance ≤ 6 mm.

resultsIn group 2, shorter ablation time (12.5 ± 3.8 vs 17 ± 7 min, p = 0.049), overall RF application time (7.9 ± 1.4 vs 10.8 ± 3.2 min. p = 0.01) and less radiofrequency (RF) applications (14.5 ± 2.3 vs 20.5 ± 6.1 p = 0.01) were necessary to achieve AL bi-directional block. Acute reconnection of the AL was documented in three patients (20%) of group 1 and in no patient of group 2 (20% vs 0% p = 0.22). At site of reconnection, an inter-lesion distance > 6 mm was always found. There was no difference in terms of CF and power between group 2 and group 1. AI was statistically different between group 2 and group 1 (AI = 511 ± 77 vs 451 ± 111; p = 0.004).

conclusionAI-guided LAALA in this study was feasible and featured by shorter ablation time, shorter overall RF application time and a reduced number of RF applications to achieve AL bidirectional block.

Indexed as

AgedAtrial FibrillationCatheter AblationFemaleHeart AtriaHumansMaleRetrospective StudiesTachycardiaTime FactorsTreatment OutcomeAblationAblation indexAnterior lineContact forcePowerPulmonary vein isolationPVIRF

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.