Evidence map›Paper›PMID 30712133›Full record

ArticleLung2019

Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep.

Andras Bikov, Zsofia Lazar, Peter Horvath, David Laszlo Tarnoki, Adam Domonkos Tarnoki, Luca Fesus, Marton Horvath, Martina Meszaros, Gyorgy Losonczy, Laszlo Kunos

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Lung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. REM sleep obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dyslipidemia prevalence in nonobese, nondiabetic patients with obstructive sleep apnea: does sex matter?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Andras BikovDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary. andras.bikov@gmail.com.ORCID 0000-0002-8983-740X
Zsofia LazarDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Peter HorvathDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
David Laszlo TarnokiDepartment of Radiology, Semmelweis University, 78/A Ulloi ut, Budapest, 1082, Hungary.
Adam Domonkos TarnokiDepartment of Radiology, Semmelweis University, 78/A Ulloi ut, Budapest, 1082, Hungary.
Luca FesusDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Marton HorvathDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Martina MeszarosDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Gyorgy LosonczyDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Laszlo KunosDepartment of Pulmonology, Semmelweis University, 1/C Dios arok, Budapest, 1125, Hungary.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObstructive sleep apnoea (OSA) represents a risk for dyslipidaemia. Obstructive respiratory events during rapid eye movement (REM) sleep are more strongly related to the development of hypertension and diabetes than in non-REM. However, the relationship between sleep phases and serum lipid profile is unclear. We aimed to analyse the relationship between obstructive respiratory events in REM and non-REM sleep as well as serum lipid profile.

methodsPolysomnography was performed in 94 adult subjects who did not take any lipid-modifying medications. Fasting venous blood sample was taken the following morning for total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, lipoprotein(a), apoprotein A1 (ApoA1) and for apoprotein B (ApoB) measurements. Lipid profiles were correlated with apnoea-hypopnoea index (AHI) during REM (AHI

resultsAHI

conclusionsAltered serum lipid profile is equally associated with a disturbed REM and non-REM sleep in OSA. Obesity must be considered as a strong covariate when interpreting lipid data in sleep apnoea.

Indexed as

RespirationSleep, REMAdultAgedBiomarkersCase-Control StudiesDyslipidemiasFemaleHumansLipidsLungMaleMiddle AgedRisk FactorsSleep Apnea, ObstructiveBiomarkersLipidsApolipoproteinsDyslipidaemiaLipidsObstructive sleep apnoeaREM sleep

Identifiers

PMID30712133
PMCPMC6647223
OpenAlexW2914356024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.