ArticleSkeletal radiology2019
T2 mapping of cartilage and menisci at 3T in healthy subjects with knee malalignment: initial experience.
Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Quantitative Magnetic Resonance Imaging of Femoral Head Articular Cartilage Change in Patients with Hip Osteonecrosis Treated with Extracorporeal Shock Wave Therapy.International journal of clinical practice · 2022Trial
- Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T: regional values, longitudinal repeatability and method agreement.Quantitative imaging in medicine and surgery · 2026Article
- Knee Cartilage Quantification: Performance of Low-Field MR in Detecting Low Grades of Chondropathy.Journal of imaging · 2025Article
- Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players.BMC musculoskeletal disorders · 2024Article
- Multi-frame biomechanical and relaxometry analysis during in vivo loading of the human knee by spiral dualMRI and compressed sensing.Magnetic resonance in medicine · 2023Article
- T2 mapping for knee cartilage degeneration in young patients with mild symptoms.BMC medical imaging · 2022Article
- TSkeletal radiology · 2022Article
- Relationship Between Magnetic Resonance T2-Mapping and Matrix Metalloproteinase 1,3 in Knee Osteoarthritis.Indian journal of orthopaedics · 2021Article
- 3-T MRI mapping is a valid in vivo method of quantitatively evaluating the anterior cruciate ligament: rater reliability and comparison across age.Skeletal radiology · 2020Article
- T2 distribution profiles are a good way to show cartilage regional variabilities and cartilage insufficiency.Skeletal radiology · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo assess the relationship between knee alignment and T2 values of femorotibial cartilage and menisci in healthy subjects at 3 T. MATERIALS AND
methodsThirty-six healthy subjects divided into three subgroups of 12 neutral, 12 varus, and 12 valgus alignment of the femorotibial joint were investigated on 3-T MR scanner using a 2D multi-echo turbo spin-echo (TSE) sequence for T2 mapping. Wilcoxon signed-rank test and analysis of covariance (ANCOVA) were performed to determine any statistically significant differences in subregional T2 values of femorotibial cartilage and menisci among the three subgroups of healthy subjects.
resultsLateral femoral anterior cartilage subregion (52 ± 3 ms, mean ± standard deviation; 53 ± 2 ms) had significantly higher T2 values (p < 0.05) than medial femoral anterior cartilage subregion (51 ± 2 ms; 51 ± 2 ms) in varus and valgus groups, respectively. There were statistically significant differences (p < 0.05) in T2 values of tibial central cartilage subregion between lateral and medical compartment among varus, valgus, and neutral subgroups. Lateral body segment of meniscus (41 ± 3 ms) had significantly higher (p < 0.05) T2 values than medial body segment (40 ± 2 ms) in the varus subgroup.
conclusionsSome degree of correlation between knee alignment and subregional T2 values of femorotibial cartilage and menisci exists in healthy subjects. These findings indicate that T2 mapping may be sensitive in assessing the load distribution pattern of human cartilage and menisci with knee alignment abnormality, which may be used as reference baseline when understanding the occurrence and progression of knee osteoarthritis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.