Evidence map›Paper›PMID 30712099›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

Incidence and severity of sexual dysfunction among women with breast cancer: a meta-analysis based on female sexual function index.

Liwei Jing, Chao Zhang, Wei Li, Feng Jin, Aiping Wang

Registry-linked trialAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06458764 (SEXCHECK - Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy), which is not on this map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06458764 unknown statusnot on this mapstarted 2023, after this paper: background citation

SEXCHECK - Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy: A Cross-Sectional Study

Typeobservational_patient_registrySponsorCandiolo Cancer Institute - IRCCSRan2023 to 2025Enrolled150ConditionsBreast Cancer Female, Sexual Dysfunction, Premenopausal Breast CancerArmsQuestionnaire
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Sexual dysfunction in women with breast cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Sexual Dysfunction in Women with Cancer: A Systematic Review of Longitudinal Studies.International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. The effects of staged sexual health education on sexual and mental health in breast cancer patients: a randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  8. Trial
  9. Article
  10. Sexual health among patients with breast cancer undergoing endocrine therapy: an integrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  11. Article
  12. Breast cancer survivor's sexual health unmet supportive care needs: a mixed-methods study.Journal of cancer survivorship : research and practice · 2026
    Article
  13. Article
  14. More than just "vaginal dryness": sexual dysfunction correlates with genitourinary anatomy changes in female cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  15. Article
  16. The relationship between sexual activity during chemotherapy and sexual functioning after treatment among females with breast and gynecologic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  17. Article
  18. Review
  19. Sexual dysfunction and its impact on quality of life among female haematological cancer patients: a cross-sectional study in Malaysia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Liwei JingNational Academy of Development and Strategy, Renmin University of China, No. 59 Zhongguancun Street, Haidian District, Beijing, 100872, China.
Chao ZhangAffiliated Hospital of North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Wei LiRadiotherapy Department, Tangshan People's Hospital, No.65 Shengli Road, Lunan District, Tangshan, 063001, Hebei, China.
Feng JinBreast Surgery, First Affiliated Hospital of China Medical University, Heping District, Nanjing street, No. 155, Shenyang, 110001, Liaoning, China.
Aiping WangDepartment of Nursing, First Affiliated Hospital of China Medical University, Heping District, Nanjing street, No. 155, Shenyang, 110001, Liaoning, China. jianghaoran88@hotmail.com.
China Medical University · CNNorth China University of Science and Technology · CNRenmin University of China · CN

Funding

National Natural Science Foundation of China (CN) No. 81803106Ph.D. Foundation of North China University of Science and Technology No. BS2017057
6 · The paper itself

Abstract

purposePrevious meta-analyses have examined the prevalence of sexual dysfunction among women with cancer, but there is no breast cancer (BC)-specific study. We therefore conducted a meta-analysis to examine the prevalence and severity of female sexual dysfunction (FSD) in women with BC.

methodsWe searched PubMed, Embase, Cochrane Library, CNKI, WanFang Data, and VIP for relevant studies published between April 2000 and January 2017. Data were extracted from studies which assessed FSD prevalence and sexual function in women with BC using the female sexual function index (FSFI). Meta-analyses were performed by pooling the prevalence rates of FSD and total FSFI scores. Meta regression was performed to explore the sources of heterogeneity.

resultsWe selected 19 published studies involving a total of 2684 women with BC. In this study population, overall FSD prevalence was 73.4% (95% confidence interval (CI) 64.0%, 82.8%), and the total FSFI score was 19.28 (95% CI 17.39, 21.16). Among Asian, American, and European women with BC, there were significant differences in FSD prevalence (P < 0.001), and there was marginally significant difference (P = 0.07) in sexual function between these groups. There was also a marginally significant difference between individuals from mainland China and from other countries in FSD prevalence (P = 0.06) and FSFI score (P = 0.07).

conclusionsOverall, women with BC have high FSD prevalence and low sexual function. American women with BC have a higher average FSD prevalence and lower average sexual function than Asian women with BC. The FSD prevalence in women with BC in mainland China was slightly higher than in other countries.

Indexed as

Health Status IndicatorsAdultAgedBreast NeoplasmsChinaFemaleHumansIncidenceMiddle AgedPrevalenceSeverity of Illness IndexSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalBreast cancerFemale sexual dysfunctionFemale sexual function indexMeta-analysisPrevalence

Identifiers

PMID30712099
OpenAlexW2914178430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.