Evidence map›Paper›PMID 30712076›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020

Use of left atrial appendage occlusion among older cardiac surgery patients with preoperative atrial fibrillation: a national cohort study.

Daniel J Friedman, Jeffrey G Gaca, Tongrong Wang, S Chris Malaisrie, David R Holmes, Jonathan P Piccini, Rakesh M Suri, Michael J Mack, Vinay Badhwar, Jeffrey P Jacobs and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Sex Differences in Atrial Fibrillation.Current cardiology reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Daniel J FriedmanDuke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA.
Jeffrey G GacaDivision of Cardiovascular and Thoracic Surgery, Duke University, Durham, NC, 27710, USA.
Tongrong WangDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, 27710M, USA.
S Chris MalaisrieDivision of Cardiac Surgery, Northwestern University, Chicago, IL, 60611, USA.
David R HolmesDivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
Jonathan P PicciniDuke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA.
Rakesh M SuriDivision of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Michael J MackDivision of Cardiovascular Surgery, Baylor University, Dallas, TX, 75246, USA.
Vinay BadhwarDepartment of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, WV, 26506, USA.
Jeffrey P JacobsHopkins All Children's Heart Institute, Saint Petersburg, FL, 33701, USA.
Eric D PetersonDuke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA.
Shein-Chung ChowDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, 27710M, USA.
J Matthew BrennanDuke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA. j.matthew.brennan@dm.duke.edu.
Clinical Research Institute · USDuke University · USMayo Clinic in Arizona · USBaylor University · USJohns Hopkins All Children's Hospital · USNorthwestern University · USWest Virginia University · US

Funding

Postdoctoral Training in Cardiovascular Clinical ResearchT32HL069749 · NHLBI · DUKE UNIVERSITY · PI MARK, DANIEL B · 2003 to 2023
$6.7M
FDA HHS U01 FD004591National Institutes of Health (US) T 32 training grant HL069749NHLBI NIH HHS T32 HL069749U.S. Food and Drug Administration 1U01FD004591-01
6 · The paper itself

Abstract

purposePatients with atrial fibrillation (AF) undergoing cardiac surgery are at substantially increased risk for stroke. Increasing evidence has suggested that surgical left atrial appendage occlusion (S-LAAO) may have the potential to substantially mitigate this stroke risk; however, S-LAAO is performed in a minority of patients with AF undergoing cardiac surgery. We sought to identify factors associated with usage of S-LAAO.

methodsIn a nationally-representative, contemporary cohort (07/2011-06/2012) of older patients undergoing cardiac surgery with preoperative AF (n = 11,404) from the Medicare-linked Society of Thoracic Surgeons Adult Cardiac Surgery Database, we evaluated patient and hospital characteristics associated with S-LAAO use by employing logistic and linear regression models.

resultsIn this cohort (average age, 76 years; 39% female), 4177 (37%) underwent S-LAAO. Neither S-LAAO nor discharge anticoagulation was used in 25% ("unprotected" patients). The overall propensity for S-LAAO decreased significantly with increasing CHA

conclusionsSubstantial variability in use of S-LAAO exists. In many instances, the procedure is being deferred in the patients that may be poised to benefit the most (i.e., those with increased CHA

Indexed as

Cardiac Surgical ProceduresAgedAtrial AppendageAtrial FibrillationFemaleHumansMaleRisk FactorsStrokeArrhythmia therapy (including ablationAtrial fibrillationAtrial flutterDrugs)Surgery

Identifiers

PMID30712076
PMCPMC9903467
OpenAlexW2914950707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.