ArticleDiagnostic pathology2019
Pathological diagnosis of thyroid nodules based on core needle biopsies: comparative study between core needle biopsies and resected specimens in 578 cases.
Article in Diagnostic pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy.Journal of pathology and translational medicine · 2023Review
- Application of biomarkers in the diagnosis of uncertain samples of core needle biopsy of thyroid nodules.Virchows Archiv : an international journal of pathology · 2021Article
- Core-Needle Biopsy Does Not Show Superior Diagnostic Performance to Fine-Needle Aspiration for Diagnosing Thyroid Nodules.Yonsei medical journal · 2020Article
- 2019 Practice guidelines for thyroid core needle biopsy: a report of the Clinical Practice Guidelines Development Committee of the Korean Thyroid Association.Journal of pathology and translational medicine · 2020Review
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Authors and funding
5 authors.
Funding
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Abstract
backgroundPathological diagnosis based on core needle biopsy (CNB) should be different from a resected specimen because it is difficult to apply the histological criteria established for resected specimens to CNB due to sampling limitations. A pathological classification for thyroid nodule on CNB was first proposed by the Korean Group in 2015. The objective of this study was to test the reliability and clinical value of this proposal.
methodsAccording to the Korean proposal, the CNB diagnoses were categorized into unsatisfactory, benign, indeterminate, follicular neoplasm, suspicious for malignancy and malignant. A comparative study between the diagnoses of CNB and resected specimens was performed.
resultsThe consistency was moderate (κ = 0.448). Combined indeterminate, suspicious for malignancy and malignant into a single group collectively referred to as "malignant" with the remaining merged into "others", CNB demonstrated a 95.93% sensitivity, 97.30% specificity, 62.07% accuracy, 99.81% positive predictive value (PPV) and 62.07% negative predictive value (NPV) for preoperative malignancy evaluation.
conclusionsThe Korean proposal for pathological classification of thyroid nodules on CNB is objective, operable and highly valuable.
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