Evidence map›Paper›PMID 30710800›Full record

ArticleVirology2019

Porcine sapelovirus enters PK-15 cells via caveolae-dependent endocytosis and requires Rab7 and Rab11.

Tingting Zhao, Li Cui, Xiangqian Yu, Zhonghai Zhang, Xiaojuan Shen, Xiuguo Hua

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Lung Endothelial Transcytosis.Comprehensive Physiology · 2020
    Review
  5. Dynamics of transmissible gastroenteritis virus internalization unraveled by single-virus tracking in live cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tingting ZhaoShanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China.
Li CuiShanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China.
Xiangqian YuShanghai Pudong New Area Center for Animal Disease Control and Prevention, Shanghai 200136, China.
Zhonghai ZhangShanghai Pudong New Area Center for Animal Disease Control and Prevention, Shanghai 200136, China.
Xiaojuan ShenShanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China.
Xiuguo HuaShanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China. Electronic address: hxg@sjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To comprehensively understand the endocytosis of Sapelovirus A (PSV) entry into PK-15 cells, we studied PSV infection in the context of cell perturbations through drug inhibition, siRNA silencing and overexpression of dominant negative (DN) mutants. We showed here that PSV infection of PK-15 cells was unaffected by pretreated with chlorpromazine, EIPA, knockdown of the clathrin heavy chain or overexpression of Eps15 DN mutant. Conversely, PSV infection was sensitive to NH

Indexed as

Virus InternalizationAnimalsCaveolaeCell LineCell SurvivalEndocytosisHydrogen-Ion ConcentrationPicornaviridaerab11 GTP-Binding Proteinsrab7 GTP-Binding Proteinsrab GTP-Binding ProteinsSwinerab11 GTP-Binding Proteinsrab7 GTP-Binding Proteinsrab GTP-Binding ProteinsCaveolaeEndocytosisSapelovirusVirus entry

Identifiers

PMID30710800
PMCPMC7125664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.