ArticleNeuroImage2019
Multi-modal neuroimaging of dual-task walking: Structural MRI and fNIRS analysis reveals prefrontal grey matter volume moderation of brain activation in older adults.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- A Systematic Review of the Application of Functional Near-Infrared Spectroscopy to the Study of Cerebral Hemodynamics in Healthy Aging.Neuropsychology review · 2021Pooled it
- Effects of Prefrontal Transcranial Direct Current Stimulation on Retention of Performance Gains on an Obstacle Negotiation Task in Older Adults.Neuromodulation : journal of the International Neuromodulation Society · 2023Trial
- Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial.Neuromodulation : journal of the International Neuromodulation Society · 2021Trial
- Is self-report brain fog after mild COVID-19 truly induced by COVID-19 infection? A longitudinal fNIRS study.Dialogues in clinical neuroscience · 2026Article
- Mapping the evolution of dual-task paradigms in cognitive aging: A bibliometric analysis of research landscapes and translational applications.GeroScience · 2026Review
- Neurovascular decoupling and compensatory network recruitment during speech perception in aging: evidence from EEG-fNIRS.GeroScience · 2026Article
- Cortical activation, gait performance, and muscle activation during dual-task walking in older adults with mild cognitive impairment.BMC geriatrics · 2026Article
- How aging impacts cortical dynamics and gait during dual-task turning revealed by fNIRS.GeroScience · 2026Article
- The ageing brain: Cortical overactivation - How does it evolve?The Journal of physiology · 2026Review
- Neural Correlates of Inhibitory Control in Children: Evidence Using MRI and fNIRS.Brain topography · 2025Article
- Differences in brain function entropy due to cognitive impairment: Application of functional near infrared spectroscopy measures during dual-tasking.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025Article
- Gait Characteristics and Neuroanatomical Alterations in Obstructive Sleep Apnea-Hypopnea Syndrome.Nature and science of sleep · 2025Article
- Association of Compensatory Mechanisms in Prefrontal Cortex and Impaired Anatomical Correlates in Semantic Verbal Fluency: A Functional Near-Infrared Spectroscopy Study.Psychiatry investigation · 2024Article
- Comparative analysis of the effects of the computer-based and paper-based trail making tests on oxygenation in the prefrontal cortex.BMC neuroscience · 2024Article
- Prefrontal cortex activation under stress as a function of borderline personality disorder in female adolescents engaging in non-suicidal self-injury.BJPsych open · 2024Article
- Brain control of dual-task walking can be improved in aging and neurological disease.GeroScience · 2024Article
- The impact of music making on neural efficiency & dual-task walking performance in healthy older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2024Article
- Cortical thickness moderates intraindividual variability in prefrontal cortex activation patterns of older adults during walking.Journal of the International Neuropsychological Society : JINS · 2024Article
- Reduced Proactive and Reactive Cognitive Flexibility in Older Adults Underlies Performance Costs During Dual-Task Walking: A Mobile Brain/Body Imaging (MoBI) Study.bioRxiv : the preprint server for biology · 2024Article
- The prefrontal cortex hemodynamic responses to dual-task paradigms in older adults: A systematic review and meta-analysis.Heliyon · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
It has been well established over the last two decades that walking is not merely an automatic, motoric activity; it also utilizes executive function circuits, which play an increasingly important role in walking for older people and those with mobility and cognitive deficits. Dual-task walking, such as walking while performing a cognitive task, is a necessary skill for everyday functioning, and has been shown to activate prefrontal lobe areas in healthy older people. Another well-established point in healthy aging is the loss of grey matter, and in particular loss of frontal lobe grey matter volume. However, the relationship between increased frontal lobe activity during dual-task walking and loss of frontal grey matter in healthy aging remains unknown. In the current study, we combined oxygenated hemoglobin (HbO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.