Evidence map›Paper›PMID 30710381›Full record

ArticleMedical physics2019

Patient body motion correction for dynamic cardiac PET-CT by attenuation-emission alignment according to projection consistency conditions.

Chad R R N Hunter, Ran Klein, Adam M Alessio, Robert A deKemp

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Diagnosis of multivessel coronary artery disease usingJapanese journal of radiology · 2026
    Article
  2. Beyond stillness: the importance of tackling patient's motion for reliable parametric imaging.European journal of nuclear medicine and molecular imaging · 2024
    Article
  3. Article
  4. Article
  5. Quantification of myocardial blood flow by CZT-SPECT with motion correction and comparison withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Chad R R N HunterCarleton University, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Ran KleinCarleton University, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Adam M AlessioMichigan State University, 775 Woodlot Drive, East Lansing, MI, 48824, USA.
Robert A deKempCarleton University, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Carleton University · CAMichigan State University · USOttawa Hospital · CAUniversity of Ottawa · CA

Funding

Low-dose Myocardial Perfusion Imaging by CTR01HL109327 · NHLBI · UNIVERSITY OF WASHINGTON · PI ALESSIO, ADAM M · 2012 to 2017
$2.2M
Natural Sciences and Engineering Research Council of Canada 436149NHLBI NIH HHS R01 HL109327Ontario Research Fund ORF-RE02-038Ontario Research Fund ORF-RE07-021
6 · The paper itself

Abstract

introductionPatient body motion is known to cause large deviations in the determination of myocardial blood flow (MBF) with errors exceeding 300%. Accurate correction for patient whole-body motion is still a largely unsolved problem in cardiac positron emission tomography (PET) imaging.

objectiveThis study evaluated the efficacy of using Natterer's formulation of the Helgason-Ludwig consistency conditions on the two-dimensional Radon transform to align computed tomography to PET projection data in multiple time frames of a dynamic sequence for the purpose of frame-by-frame correction of rigid whole-body motion.

methodsThe correction algorithm was evaluated with digital NCAT phantoms using realistic noise added by the analytical simulator. Count rates used in the simulation were derived from clinical patient data. In addition, a proof of concept test using measured data with a cardiac torso phantom was conducted.

resultsMotion correction resulted in significant improvement in the accuracy of MBF estimates, especially for high count-rate acquisitions. Maximum errors for 2 cm of motion dropped from 325% to 25% and from 250% to 25% using global and regional partial-volume correction, respectively. Median MBF errors dropped from 33% to 4.5% and 27% to 3.8%, respectively. Importantly, the correction algorithm performed equally well to compensate for body motion in both early and late time frames.

conclusionCardiac PET-CT data used for attenuation correction (CTAC) alignment using projection consistency conditions was effective for reducing errors in MBF measurements due to simulated patient motion, and can be integrated into the image reconstruction workflow.

Indexed as

AlgorithmsMovementPhantoms, ImagingArtifactsHeartHumansImage Processing, Computer-AssistedModels, CardiovascularPositron Emission Tomography Computed TomographyRespirationdynamic positron emission tomographymotion correctionpatient body motion

Identifiers

PMID30710381
PMCPMC9559704
OpenAlexW2914315180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.