Evidence map›Paper›PMID 30710274›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Gene Transfer of Calcium-Binding Proteins into Adult Cardiac Myocytes.

Brian R Thompson, Houda Cohen, Addeli Bez Batti Angulski, Joseph M Metzger

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Disease markers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brian R ThompsonDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN, USA.
Houda CohenDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN, USA.
Addeli Bez Batti AngulskiDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN, USA.
Joseph M MetzgerDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN, USA. metzgerj@umn.edu.
University of Minnesota Medical Center · US

Funding

Myofilaments as regulators of heart function in diseaseR01HL132874 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2017 to 2025
$3.7M
Copolymer-Based Sarcolemma Stabilization for Protecting Dystrophic Skeletal Muscles in VivoR01AR071349 · NIAMS · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2018 to 2022
$2.3M
Dystrophin Function in Aging HeartR01AG034107 · NIA · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2010 to 2014
$1.7M
Dystrophin and Heart DiseaseR01HL138490 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2017 to 2020
$1.5M
NHLBI NIH HHS R01 HL132874NHLBI NIH HHS R01 HL138490NIAMS NIH HHS R01 AR071349NIA NIH HHS R01 AG034107
6 · The paper itself

Abstract

Heart failure is the leading cause of combined morbidity and mortality in the USA with 50% of cases being diastolic heart failure. Diastolic heart failure results from poor myocardial relaxation and inadequate filling of the left ventricular chamber caused in part by calcium-handling dysregulation. In this chapter we describe methods to investigate new approaches of novel human Ca

Indexed as

Gene Transfer TechniquesAdenoviridaeAdultAnimalsCalciumCalcium-Binding ProteinsFemaleGenetic VectorsHeart FailureHeart VentriclesHumansModels, BiologicalMutationMyocytes, CardiacParvalbuminsRats, Sprague-DawleyCalciumCalcium-Binding ProteinsParvalbuminsAdult cardiac myocyteCalciumCalcium imagingContractilityGene transferParvalbumin

Identifiers

PMID30710274
PMCPMC6507422
OpenAlexW2913212950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.