Evidence map›Paper›PMID 30710223›Full record

ArticleCurrent topics in behavioral neurosciences2021

Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature.

David E Vance, Pariya L Fazeli, John Cheatwood, Chance Nicholson, Shannon Morrison, Linda D Moneyham

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Current topics in behavioral neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05598047 phase2completednot on this mapstarted 2023, after this paper: background citation

Executive Function Training to Reduce Cognitive Intra-Individual Variability in Adults With HIV

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2023 to 2025Enrolled119ConditionsAging, Cognitive Function Abnormal, Cognitive Performance, Cognitive TrainingArmsExecutive Functioning Training
NCT05773430 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Reducing Cognitive Intra-Individual Variability and Cognitive Impairment in Adults With HIV (The Targeted Neurocognitive Training (TNT) Study)

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2026 to 2027Enrolled0ConditionsHIV, Aging, Cognitive Function Abnormal, Cognitive TrainingArmsTargeted Neurocognitive Training
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA. devance@uab.edu.
Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
John CheatwoodSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Chance NicholsonSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Shannon MorrisonSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Linda D MoneyhamSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 50% of older adults with HIV meet the Frascati diagnostic criteria of HIV-associated neurocognitive disorders (HAND) which can interfere with everyday function such as medication adherence, employment, and driving ability, thus reducing quality of life. As the number of older adults with HIV continues to grow, many will become vulnerable to cognitive frailty, especially as they experience multimorbidities, polypharmacy, and geriatric syndromes. Healthcare professionals need strategies to prevent, remediate, and compensate for cognitive losses observed in memory, language, executive functioning, and speed of processing. Sadly, there are no standard protocols or accepted treatment/intervention guidelines to address HAND at this time. Fortunately, evidence from the cognitive aging literature indicates that cognitive training can protect and improve cognition in normal older adults and may even reduce the incidence of dementia/MCI. This article provides the scientific context in which computerized cognitive training approaches have been successfully used in older adults and provides examples of how these approaches have been translated to adults with HIV. Evidence from ongoing clinical trials are also presented that suggest that reversing a diagnosis of HAND may be possible. Recommendations for clinical practice and research are provided.

Indexed as

Cognitive AgingHIV InfectionsAgedCognitionHumansNeurocognitive DisordersQuality of LifeCognitive agingCognitive efficiencyCognitive trainingHIV/AIDSNeuroHIVNeuroplasticity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.