Evidence map›Paper›PMID 30710214›Full record

ArticleMolecular neurobiology2019

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases.

Elisa Meneghetti, Lisa Gasperini, Tommaso Virgilio, Fabio Moda, Fabrizio Tagliavini, Federico Benetti, Giuseppe Legname

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  3. Article
  4. New Light on Prions: Putative Role of PrPInternational journal of molecular sciences · 2024
    Review
  5. Post-translational modifications in prion diseases.Frontiers in molecular neuroscience · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elisa MeneghettiLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy.
Lisa GasperiniLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy.
Tommaso VirgilioFondazione IRCCS Istituto Neurologico Carlo Besta, Unit of Neuropathology and Neurology-5, Milano, Italy.
Fabio ModaFondazione IRCCS Istituto Neurologico Carlo Besta, Unit of Neuropathology and Neurology-5, Milano, Italy.
Fabrizio TagliaviniFondazione IRCCS Istituto Neurologico Carlo Besta, Scientific Directorate, Milano, Italy.
Federico BenettiLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy.
Giuseppe LegnameLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy. legname@sissa.it.
Fondazione IRCCS Istituto Neurologico Carlo Besta · ITScuola Internazionale Superiore di Studi Avanzati · ITElettra-Sincrotrone Trieste S.C.p.A. · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prion diseases are fatal neurodegenerative disorders characterized by the cellular prion protein (PrP

Indexed as

AnimalsEndopeptidase KFemaleHippocampusMiceModels, BiologicalNitrosationPrion DiseasesPrionsReceptors, N-Methyl-D-AspartateEndopeptidase KPrionsReceptors, N-Methyl-D-AspartateCopperExcitotoxicityNitric oxideNMDA receptorPrionsS-Nitrosylation

Identifiers

PMID30710214
OpenAlexW2913487759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.