Evidence map›Paper›PMID 30710091›Full record

ArticleNature communications2019

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.

Keiko Yasuda, Yohko Kitagawa, Ryoji Kawakami, Yoshitaka Isaka, Hitomi Watanabe, Gen Kondoh, Terumi Kohwi-Shigematsu, Shimon Sakaguchi, Keiji Hirota

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Dissecting PGENature communications · 2026
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  8. Article
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  11. Review
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  14. Article
  15. Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. A Review of Gut Microbiota-Derived Metabolites in Tumor Progression and Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Keiko YasudaLaboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Yohko KitagawaDepartment of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
Ryoji KawakamiDepartment of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
Yoshitaka IsakaDepartment of Nephrology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.
Hitomi WatanabeLaboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Gen KondohLaboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Terumi Kohwi-ShigematsuDepartment of Orofacial Sciences, University of California, San Francisco, CA 94143, USA.
Shimon SakaguchiLaboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. shimon@ifrec.osaka-u.ac.jp.
Keiji HirotaDepartment of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan. hkeiji@infront.kyoto-u.ac.jp.
Osaka University · JPKyoto University · JPUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome organizer, special AT-rich sequence-binding protein-1 (Satb1), plays a pivotal role in the regulation of global gene networks in a cell type-dependent manner and is indispensable for the development of multiple cell types, including mature CD4

Indexed as

AnimalsBiomarkersEncephalitisEncephalomyelitis, Autoimmune, ExperimentalGene Expression RegulationGenetic LociInflammationLymphocyte ActivationMatrix Attachment Region Binding ProteinsMice, Inbred C57BLMice, KnockoutProgrammed Cell Death 1 ReceptorPromoter Regions, GeneticProtein BindingSpinal CordTh17 CellsBiomarkersMatrix Attachment Region Binding ProteinsProgrammed Cell Death 1 ReceptorSatb1 protein, mouse

Identifiers

PMID30710091
PMCPMC6358604
OpenAlexW2914518033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.