Evidence map›Paper›PMID 30709899›Full record

ArticleJournal of lipid research2019

Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid.

Kyoung-Jae Won, Joo-Seop Park, Hyunyoung Jeong

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kyoung-Jae WonDepartments of Pharmacy Practice College of Pharmacy, University of Illinois at Chicago, Chicago, IL.
Joo-Seop ParkDivisions of Pediatric Urology Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH; Developmental Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH.
Hyunyoung JeongDepartments of Pharmacy Practice College of Pharmacy, University of Illinois at Chicago, Chicago, IL; Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL. Electronic address: yjeong@uic.edu.
University of Illinois Chicago · USUniversity of Cincinnati · US

Funding

Pharmacogenetic Risks Operating in Failure Of Nifedipine to Delay Pre-Term Birth (PROFOUND-PTB)R01HD089455 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI JEONG, HYUNYOUNG · 2017 to 2021
$3.4M
Cell Fate Regulation of Nephron ProgenitorsR01DK100315 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI PARK, JOO-SEOP · 2014 to 2018
$1.7M
Molecular basis of interindividual variability in CYP2D6-mediated drug metabolismR01GM112746 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI JEONG, HYUNYOUNG · 2015 to 2018
$1.2M
NICHD NIH HHS R01 HD089455NIDDK NIH HHS R01 DK100315NIGMS NIH HHS R01 GM112746
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cells, CulturedCholesterolCholesterol 7-alpha-HydroxylaseDose-Response Relationship, DrugDyslipidemiasHepatocyte Nuclear Factor 4HumansPromoter Regions, GeneticTranscription Factor AP-1TretinoinCholesterolCholesterol 7-alpha-HydroxylaseCYP7A1 protein, humanHepatocyte Nuclear Factor 4Transcription Factor AP-1Tretinoincholesterol metabolismcytochrome P450nuclear receptorsretinoids/vitamin Atoxicology

Identifiers

PMID30709899
PMCPMC6446710
OpenAlexW2912347823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.