Evidence map›Paper›PMID 30709848›Full record

ArticleGenetics2019

Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in

Christine J Smoyer, Sarah E Smith, Jennifer M Gardner, Scott McCroskey, Jay R Unruh, Sue L Jaspersen

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christine J SmoyerStowers Institute for Medical Research, Kansas City, Missouri 64110.
Sarah E SmithStowers Institute for Medical Research, Kansas City, Missouri 64110.
Jennifer M GardnerStowers Institute for Medical Research, Kansas City, Missouri 64110.
Scott McCroskeyStowers Institute for Medical Research, Kansas City, Missouri 64110.
Jay R UnruhStowers Institute for Medical Research, Kansas City, Missouri 64110.ORCID 0000-0003-3077-4990
Sue L JaspersenStowers Institute for Medical Research, Kansas City, Missouri 64110 slj@stowers.org.ORCID 0000-0001-8312-7063
Stowers Institute for Medical Research · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inner nuclear membrane (INM) protein composition regulates nuclear function, affecting processes such as gene expression, chromosome organization, nuclear shape, and stability. Mechanisms that drive changes in the INM proteome are poorly understood, in part because it is difficult to definitively assay INM composition rigorously and systematically. Using a split-GFP complementation system to detect INM access, we examined the distribution of all C-terminally tagged

Indexed as

Membrane ProteinsNuclear EnvelopeNuclear Pore Complex ProteinsProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUbiquitinationASI1 protein, S cerevisiaeMembrane ProteinsNuclear Pore Complex ProteinsPom33 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsAsi1ERADinner nuclear membraneNPCPom33split-GFP

Identifiers

PMID30709848
PMCPMC6456303
OpenAlexW2914982088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.